Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SB4_14745Hydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (219 aa)    
Predicted Functional Partners:
rpmJ
50S ribosomal protein L36; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial ribosomal protein bL36 family.
     
 0.872
guaB
Inosine-5-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
 0.825
SB4_08030
Riboflavin biosynthesis protein RibD; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 0.815
SB4_14755
Lipoprotein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.719
SB4_14760
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.605
glk
Glucokinase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the bacterial glucokinase family.
     
  0.593
SB4_14895
Dehydrogenase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
  0.593
SB4_05045
Fructokinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
  0.572
SB4_03535
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
    
 
 0.565
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.562
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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