Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
SB4_16780Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology. (377 aa)    
Predicted Functional Partners:
SB4_16775
Chemotaxis protein CheY; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.989
SB4_16100
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
 0.782
SB4_00645
Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
 0.678
SB4_02890
Histidine kinase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
    
 0.635
SB4_16785
TonB-dependent receptor; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.500
nnrE
Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
       0.473
SB4_14695
Ribonuclease; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.471
SB4_14560
Fumarate hydratase; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
       0.468
SB4_03730
LuxR family transcriptional regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.414
SB4_16095
Response regulator; Derived by automated computational analysis using gene prediction method: Protein Homology.
      
 0.414
Your Current Organism:
Sphingomonas sanguinis
NCBI taxonomy Id: 33051
Other names: 13937T, ATCC 51382, CIP 104197, DSM 13885, GIFU 2397, GIFU:2397, HAMBI 2010, IFO 13937, JCM 7514, LMG 17325, LMG:17325, NBRC 13937, S. sanguinis, Sphingomonas sanguis, strain 13937
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