node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
DacC | MltB | AO065_00350 | AO065_00335 | D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.612 |
DacC | mrdA | AO065_00350 | AO065_00325 | D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.535 |
DacC | mrdB | AO065_00350 | AO065_00330 | D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.679 |
DacC | nadD | AO065_00350 | AO065_00310 | D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.411 |
DacC | proA | AO065_00350 | AO065_00305 | D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.405 |
DacC | rlmH | AO065_00350 | AO065_00320 | D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | 50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.656 |
DacC | rlpA | AO065_00350 | AO065_00340 | D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.634 |
DacC | rsfS | AO065_00350 | AO065_00315 | D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.469 |
MltB | DacC | AO065_00335 | AO065_00350 | Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | D-alanyl-D-alanine carboxypeptidase; Penicillin-binding protein 5; removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the peptidase S11 family. | 0.612 |
MltB | mrdA | AO065_00335 | AO065_00325 | Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Penicillin-binding protein 2; Catalyzes cross-linking of the peptidoglycan cell wall. Belongs to the transpeptidase family. MrdA subfamily. | 0.792 |
MltB | mrdB | AO065_00335 | AO065_00330 | Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.805 |
MltB | nadD | AO065_00335 | AO065_00310 | Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.537 |
MltB | proA | AO065_00335 | AO065_00305 | Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.526 |
MltB | rlmH | AO065_00335 | AO065_00320 | Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.641 |
MltB | rlpA | AO065_00335 | AO065_00340 | Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Hypothetical protein; Lytic transglycosylase with a strong preference for naked glycan strands that lack stem peptides. | 0.907 |
MltB | rsfS | AO065_00335 | AO065_00315 | Lytic transglycosylase; Derived by automated computational analysis using gene prediction method: Protein Homology. | Ribosome silencing factor; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. | 0.635 |
RsmA | engB | AO065_25060 | AO065_15650 | rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 0.460 |
RsmA | rlmH | AO065_25060 | AO065_00320 | rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.602 |
engB | RsmA | AO065_15650 | AO065_25060 | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | rRNA methyltransferase; Derived by automated computational analysis using gene prediction method: Protein Homology. | 0.460 |
engB | rlmH | AO065_15650 | AO065_00320 | GTP-binding protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. | 50S rRNA methyltransferase; Specifically methylates the pseudouridine at position 1915 (m3Psi1915) in 23S rRNA; Belongs to the RNA methyltransferase RlmH family. | 0.631 |