Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
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[Homology]
Score
Saci_0366Glutaconate CoA-transferase. (239 aa)    
Predicted Functional Partners:
Saci_0367
Coenzyme A transferase.
 
 0.999
cisY
Citrate synthase.
  
 0.787
Saci_0365
Conserved protein.
       0.773
acnA
Aconitate hydratase.
   
 
 0.739
Saci_1968
Conserved acetyl-CoA acetyltransferase.
 
 
 0.644
Saci_1759
acetyl-CoA acetyltransferase.
 
 
 0.643
fumC
Fumarate hydratase class II.
   
  0.630
mdh
Lactate/malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily.
  
 0.624
Saci_1071
Conserved protein; acyl-CoA dehydrogenase, C-terminal domain.
 
 
 0.618
acd
acyl-CoA dehydrogenase.
 
 
 0.596
Your Current Organism:
Sulfolobus acidocaldarius DSM 639
NCBI taxonomy Id: 330779
Other names: S. acidocaldarius DSM 639, Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770
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