STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Saci_0366Glutaconate CoA-transferase. (239 aa)    
Predicted Functional Partners:
Saci_0367
Coenzyme A transferase.
 
 0.999
Saci_0365
Conserved protein.
       0.773
als
Adenylosuccinate lyase; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.
  
  
 0.620
Saci_1814
Carboxymuconolactone decarboxylase.
  
  
 0.614
etfB
Electron transfer flavoprotein; Could be both subunits.
  
 
 0.588
pccB
propionyl-CoA carboxylase beta chain.
  
  
 0.587
Saci_0364
Transporter protein.
       0.564
Saci_0145
Thioesterase.
  
  
 0.539
citE
citryl-CoA lyase beta subunit-like protein.
     
 0.516
Saci_0940
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate). Carries out the first step of the leucine biosynthesis pathway. Also displays a low citramalate synthase activity, using pyruvate as substrate, but is unable to use 2-oxoglutarate.
  
  
 0.502
Your Current Organism:
Sulfolobus acidocaldarius DSM 639
NCBI taxonomy Id: 330779
Other names: S. acidocaldarius DSM 639, Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.