| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Saci_0612 | gimC | Saci_0612 | Saci_0605 | Conserved Archaeal protein. | Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 0.938 |
| Saci_0612 | psmA | Saci_0612 | Saci_0613 | Conserved Archaeal protein. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.894 |
| Saci_0612 | rpl15e | Saci_0612 | Saci_0617 | Conserved Archaeal protein. | 50S ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. | 0.935 |
| Saci_0612 | rrp42 | Saci_0612 | Saci_0609 | Conserved Archaeal protein. | Exosome complex exonuclease RRP43-like protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.906 |
| Saci_1501 | glpK1 | Saci_1501 | Saci_1117 | Hypothetical protein; Similar to gi:15897071. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.958 |
| Saci_1501 | glpK2 | Saci_1501 | Saci_2033 | Hypothetical protein; Similar to gi:15897071. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.958 |
| Saci_1501 | pan | Saci_1501 | Saci_0656 | Hypothetical protein; Similar to gi:15897071. | Protease regulatory protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S pro [...] | 0.998 |
| Saci_1501 | psmA | Saci_1501 | Saci_0613 | Hypothetical protein; Similar to gi:15897071. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.917 |
| Saci_1501 | psmB1 | Saci_1501 | Saci_0662 | Hypothetical protein; Similar to gi:15897071. | Proteasome protease subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.917 |
| Saci_1501 | psmB2 | Saci_1501 | Saci_0909 | Hypothetical protein; Similar to gi:15897071. | Proteasome beta subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.917 |
| gimC | Saci_0612 | Saci_0605 | Saci_0612 | Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | Conserved Archaeal protein. | 0.938 |
| gimC | psmA | Saci_0605 | Saci_0613 | Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.852 |
| gimC | rpl15e | Saci_0605 | Saci_0617 | Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | 50S ribosomal protein L15E; Belongs to the eukaryotic ribosomal protein eL15 family. | 0.624 |
| gimC | rrp42 | Saci_0605 | Saci_0609 | Prefoldin beta subunit; Molecular chaperone capable of stabilizing a range of proteins. Seems to fulfill an ATP-independent, HSP70-like function in archaeal de novo protein folding. | Exosome complex exonuclease RRP43-like protein; Non-catalytic component of the exosome, which is a complex involved in RNA degradation. Contributes to the structuring of the Rrp41 active site. | 0.848 |
| glpK1 | Saci_1501 | Saci_1117 | Saci_1501 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | Hypothetical protein; Similar to gi:15897071. | 0.958 |
| glpK1 | glpK2 | Saci_1117 | Saci_2033 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | 0.901 |
| glpK1 | pan | Saci_1117 | Saci_0656 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | Protease regulatory protein; ATPase which is responsible for recognizing, binding, unfolding and translocation of substrate proteins into the archaeal 20S proteasome core particle. Is essential for opening the gate of the 20S proteasome via an interaction with its C-terminus, thereby allowing substrate entry and access to the site of proteolysis. Thus, the C- termini of the proteasomal ATPase function like a 'key in a lock' to induce gate opening and therefore regulate proteolysis. Unfolding activity requires energy from ATP hydrolysis, whereas ATP binding alone promotes ATPase-20S pro [...] | 0.958 |
| glpK1 | psmA | Saci_1117 | Saci_0613 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | Proteasome alpha subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.853 |
| glpK1 | psmB1 | Saci_1117 | Saci_0662 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | Proteasome protease subunit; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.853 |
| glpK1 | psmB2 | Saci_1117 | Saci_0909 | Glycerol kinase; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate. | Proteasome beta subunit precursor; Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation. | 0.853 |