node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Saci_0849 | Saci_0850 | Saci_0849 | Saci_0850 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Serine/threonine protein kinase. | 0.859 |
Saci_0849 | kae1 | Saci_0849 | Saci_0851 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. | 0.883 |
Saci_0849 | rbsS27AE | Saci_0849 | Saci_0852 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 30S ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.851 |
Saci_0849 | rps15 | Saci_0849 | Saci_0829 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 30S ribosomal protein S15P. | 0.479 |
Saci_0849 | rps24e | Saci_0849 | Saci_0853 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 30S ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.860 |
Saci_0849 | thi | Saci_0849 | Saci_0854 | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. | 0.785 |
Saci_0850 | Saci_0849 | Saci_0850 | Saci_0849 | Serine/threonine protein kinase. | Nucleoside-triphosphatase; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.859 |
Saci_0850 | Saci_0965 | Saci_0850 | Saci_0965 | Serine/threonine protein kinase. | Conserved Archaeal protein. | 0.725 |
Saci_0850 | Saci_1289 | Saci_0850 | Saci_1289 | Serine/threonine protein kinase. | Conserved Archaeal protein; Operon conserved in 3 sulfolobes - two genes involved with tRNA. | 0.737 |
Saci_0850 | Saci_1477 | Saci_0850 | Saci_1477 | Serine/threonine protein kinase. | Conserved protein; Similar to gi:15921670. | 0.733 |
Saci_0850 | kae1 | Saci_0850 | Saci_0851 | Serine/threonine protein kinase. | O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is probably involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37; Belongs to the KAE1 / TsaD family. | 0.991 |
Saci_0850 | rbsS27AE | Saci_0850 | Saci_0852 | Serine/threonine protein kinase. | 30S ribosomal protein S27AE; Belongs to the eukaryotic ribosomal protein eS31 family. | 0.851 |
Saci_0850 | rpoD | Saci_0850 | Saci_0083 | Serine/threonine protein kinase. | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.618 |
Saci_0850 | rps15 | Saci_0850 | Saci_0829 | Serine/threonine protein kinase. | 30S ribosomal protein S15P. | 0.734 |
Saci_0850 | rps24e | Saci_0850 | Saci_0853 | Serine/threonine protein kinase. | 30S ribosomal protein S24E; Belongs to the eukaryotic ribosomal protein eS24 family. | 0.925 |
Saci_0850 | thi | Saci_0850 | Saci_0854 | Serine/threonine protein kinase. | Thiazole biosynthetic enzyme; Involved in the biosynthesis of the thiazole moiety of thiamine. Catalyzes the conversion of NAD and glycine to adenosine diphosphate 5-(2-hydroxyethyl)-4-methylthiazole-2-carboxylate (ADT), an adenylated thiazole intermediate, using free sulfide as a source of sulfur. | 0.785 |
Saci_0965 | Saci_0850 | Saci_0965 | Saci_0850 | Conserved Archaeal protein. | Serine/threonine protein kinase. | 0.725 |
Saci_0965 | Saci_1289 | Saci_0965 | Saci_1289 | Conserved Archaeal protein. | Conserved Archaeal protein; Operon conserved in 3 sulfolobes - two genes involved with tRNA. | 0.568 |
Saci_0965 | Saci_1477 | Saci_0965 | Saci_1477 | Conserved Archaeal protein. | Conserved protein; Similar to gi:15921670. | 0.568 |
Saci_0965 | rpoD | Saci_0965 | Saci_0083 | Conserved Archaeal protein. | DNA-directed RNA polymerase subunit D; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Belongs to the archaeal RpoD/eukaryotic RPB3 RNA polymerase subunit family. | 0.465 |