node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Saci_0900 | Saci_0902 | Saci_0900 | Saci_0902 | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | Conserved protein. | 0.601 |
Saci_0900 | Saci_0904 | Saci_0900 | Saci_0904 | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | Hypothetical protein; Similar to gi:14602184. | 0.463 |
Saci_0900 | cdc6-1 | Saci_0900 | Saci_0722 | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | Cell division control protein 6-like protein 1; Involved in regulation of DNA replication. | 0.978 |
Saci_0900 | cdc6-2 | Saci_0900 | Saci_0903 | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | Cell division control protein 6-like protein 2; Involved in regulation of DNA replication. | 0.988 |
Saci_0900 | dpo1 | Saci_0900 | Saci_1537 | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | DNA polymerase I; This polymerase possesses two enzymatic activities: DNA synthesis (polymerase) and an exonucleolytic activity that degrades single-stranded DNA in the 3'- to 5'-direction. | 0.976 |
Saci_0900 | fen | Saci_0900 | Saci_0775 | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | XPG/RAD25 related endonuclease; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. Binds the unpaired 3'-DNA end and kinks the DNA to facilitate 5' cleavage specificity. Cleaves one nucleotide into the double-stranded DNA from the junction in flap DNA, leaving a nick for ligation. Also involved in the base excision repair (BER) [...] | 0.881 |
Saci_0900 | moaC | Saci_0900 | Saci_0905 | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.465 |
Saci_0900 | priL | Saci_0900 | Saci_1542 | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | DNA primase large subunit; Regulatory subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Stabilizes and modulates the activity of the small subunit, increasing the rate of DNA synthesis, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. May also play a role in DNA repair. | 0.979 |
Saci_0900 | priS | Saci_0900 | Saci_1279 | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | DNA primase small subunit; Catalytic subunit of DNA primase, an RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. The small subunit contains the primase catalytic core and has DNA synthesis activity on its own. Binding to the large subunit stabilizes and modulates the activity, increasing the rate of DNA synthesis while decreasing the length of the DNA fragments, and conferring RNA synthesis capability. The DNA polymerase activity may enable DNA primase to also catalyze primer extension after primer synthesis. [...] | 0.960 |
Saci_0902 | Saci_0900 | Saci_0902 | Saci_0900 | Conserved protein. | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | 0.601 |
Saci_0902 | Saci_0904 | Saci_0902 | Saci_0904 | Conserved protein. | Hypothetical protein; Similar to gi:14602184. | 0.723 |
Saci_0902 | cdc6-2 | Saci_0902 | Saci_0903 | Conserved protein. | Cell division control protein 6-like protein 2; Involved in regulation of DNA replication. | 0.701 |
Saci_0902 | moaC | Saci_0902 | Saci_0905 | Conserved protein. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.682 |
Saci_0904 | Saci_0900 | Saci_0904 | Saci_0900 | Hypothetical protein; Similar to gi:14602184. | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | 0.463 |
Saci_0904 | Saci_0902 | Saci_0904 | Saci_0902 | Hypothetical protein; Similar to gi:14602184. | Conserved protein. | 0.723 |
Saci_0904 | cdc6-2 | Saci_0904 | Saci_0903 | Hypothetical protein; Similar to gi:14602184. | Cell division control protein 6-like protein 2; Involved in regulation of DNA replication. | 0.700 |
Saci_0904 | moaC | Saci_0904 | Saci_0905 | Hypothetical protein; Similar to gi:14602184. | Molybdenum cofactor biosynthesis protein C; Catalyzes the conversion of (8S)-3',8-cyclo-7,8- dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP); Belongs to the MoaC family. | 0.847 |
cdc6-1 | Saci_0900 | Saci_0722 | Saci_0900 | Cell division control protein 6-like protein 1; Involved in regulation of DNA replication. | Replication and repair minichromosome maintenance protein MCM; Belongs to the MCM family. | 0.978 |
cdc6-1 | cdc6-2 | Saci_0722 | Saci_0903 | Cell division control protein 6-like protein 1; Involved in regulation of DNA replication. | Cell division control protein 6-like protein 2; Involved in regulation of DNA replication. | 0.804 |
cdc6-1 | dnaG | Saci_0722 | Saci_0075 | Cell division control protein 6-like protein 1; Involved in regulation of DNA replication. | Conserved Archaeal protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome. | 0.709 |