STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Saci_0995Polyprenyl synthetase; Belongs to the FPP/GGPP synthase family. (283 aa)    
Predicted Functional Partners:
uppS
Undecaprenyl pyrophosphate synthetase; Generates tritrans,heptacis-undecaprenyl diphosphate from isopentenyl pyrophosphate (IPP) and geranylgeranyl diphosphate. It is probably the precursor of glycosyl carrier lipids; Belongs to the UPP synthase family.
 
 
 0.987
Saci_1734
Phytoene synthase.
  
 0.939
gds
Geranylgeranyl pyrophosphate synthetase; Catalyzes the condensation of isopentenyl pyrophosphate with the allylic pyrophosphates to yield geranylgeranyl diphosphate (GGPP) which is a precursor of the ether-linked lipids. It is able to use dimethylallyl diphosphate (DMAPP), geranyl diphosphate (GPP), and (all- E)-geranyl diphosphate (E-FPP) as an allylic substrate.
  
  
0.918
ubiA
4-hydroxybenzoate octaprenyltransferase.
 
 
 0.874
Saci_0996
Conserved protein; Similar to gi:15920701.
       0.848
mtnP
5'-methylthioadenosine phosphorylase; Catalyzes the reversible phosphorylation of S-methyl-5'- thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates; Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.
       0.848
Saci_0802
Conserved protein; Similar to hexulose-6-phosphate synthase.
     
 0.784
tatC
Translocase 6TM; Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin- arginine motif in their signal peptide across membranes.
 
   
 0.779
Saci_1688
Conserved Crenarchaeal membrane protein.
     
 0.735
Saci_0392
Conserved Archaeal membrane protein.
      
 0.733
Your Current Organism:
Sulfolobus acidocaldarius DSM 639
NCBI taxonomy Id: 330779
Other names: S. acidocaldarius DSM 639, Sulfolobus acidocaldarius ATCC 33909, Sulfolobus acidocaldarius NCIB 11770
Server load: low (26%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.