STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFUA_5G07780Squalene monooxygenase Erg1. (481 aa)    
Predicted Functional Partners:
AFUA_7G01220
Farnesyl-diphosphate farnesyltransferase, putative.
  
 
 0.996
AFUA_5G04080
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
 
 
 0.986
AFUA_4G12040
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
 
 
 0.986
AFUA_1G03950
Cytochrome P450 sterol C-22 desaturase, putaitve; Belongs to the cytochrome P450 family.
   
 
 0.984
helA
Protostadienol synthase helA; Protostadienol synthase; part of the gene cluster that mediates the biosynthesis of helvolic acid, an antibacterial nortriterpenoid. Protostadienol synthase helA cyclizes (3S)- oxidosqualene to (17Z)-protosta-17(20),24-dien-3-beta-ol (protostadienol). The synthesis of protostadienol is followed by several steps of monooxygenation, dehydrogenation, and acyl transfer to yield the final helvolic acid. Following the cyclization to the tetracyclic protostadienol by helA, cytochrome P450 monooxygenases helB1-mediated and helB2-mediated oxidation at C-4 and C-16, [...]
 
 
 0.980
AFUA_1G04720
C-8 sterol isomerase (Erg-1), putative.
   
 
 0.979
AFUA_4G04820
C-4 methyl sterol oxidase Erg25, putative; Belongs to the sterol desaturase family.
  
 
 0.968
AFUA_7G00260
Terpene cyclase/mutase family member; Belongs to the terpene cyclase/mutase family.
 
 
 
 0.968
AFUA_7G00300
Squalene-hopene-cyclase, putative.
   
 
 0.968
AFUA_5G00110
Squalene-hopene-cyclase, putative.
 
 
 
 0.968
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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