STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFUA_5G02920Nitrogen metabolite repression regulator NmrA. (352 aa)    
Predicted Functional Partners:
AFUA_6G01970
GATA transcriptional activator AreA.
    
 
 0.998
AFUA_1G12830
Nitrate reductase; Nitrate reductase is a key enzyme involved in the first step of nitrate assimilation in plants, fungi and bacteria.
      
 0.734
AFUA_1G12840
Nitrite reductase NiiA.
      
 0.733
sreA
GATA-type transcription factor sreA; GATA-type transcription repressor that regulates iron- acquisition genes through specific binding the GATA sequence element 5'-ATCWGATAA-3' of target promoters. Iron acquisition regulation is critical for survival under both iron- limiting conditions (to acquire essential iron) and iron-replete conditions (to limit iron toxicity). SreA targets include genes encoding a number of key iron-regulated factors such as those involved in siderophore biosynthesis.
    
 
 0.729
AFUA_5G10420
Nitrate reductase, putative.
      
 0.607
AFUA_6G04740
Actin Act1.
      
 0.601
AFUA_5G11560
Arp2/3 complex subunit (Arp3), putative; Belongs to the actin family.
      
 0.601
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.