STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFUA_6G12890Vacuole-associated enzyme activator complex component (Vac14), putative. (927 aa)    
Predicted Functional Partners:
AFUA_2G16640
Polyphosphoinositide phosphatase Fig4.
    
 0.985
AFUA_6G07440
1-phosphatidylinositol-3-phosphate 5-kinase (Fab1), putative.
  
 
 0.981
pam17
Presequence translocated-associated motor subunit pam17, mitochondrial; Component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.
    
 0.913
AFUA_2G08080
Phospholipid metabolism enzyme regulator, putative.
    
 0.813
AFUA_6G12910
DsDNA-dependent ATPase Rad54, putative.
 
  
   0.785
atg18
Autophagy-related protein 18; The PI(3,5)P2 regulatory complex regulates both the synthesis and turnover of phosphatidylinositol 3,5-bisphosphate (PtdIns(3,5)P2). Necessary for proper vacuole morphology. Plays an important role in osmotically-induced vacuole fragmentation. Required for cytoplasm to vacuole transport (Cvt) vesicle formation, pexophagy and starvation- induced autophagy. Involved in correct atg9 trafficking to the pre- autophagosomal structure. Might also be involved in premeiotic DNA replication (By similarity).
    
 
 0.717
AFUA_5G08670
Phosphatidylinositol 3-kinase VPS34.
     
 0.703
AFUA_5G10640
Tyrosine--tRNA ligase.
      
 0.595
AFUA_2G15940
Cofactor for methionyl-and glutamyl-tRNA synthetases, putative.
      
 0.595
AFUA_5G07340
DnaJ domain protein Psi, putative.
      
 0.592
Your Current Organism:
Aspergillus fumigatus
NCBI taxonomy Id: 330879
Other names: A. fumigatus Af293, Aspergillus fumigatus Af293
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.