node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AFUA_3G09750 | AFUA_5G06140 | Q4WXJ7 | Q4WTU6 | rRNA processing protein Utp6, putative. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.414 |
AFUA_3G09750 | AFUA_5G10470 | Q4WXJ7 | Q4WV18 | rRNA processing protein Utp6, putative. | Riboflavin aldehyde-forming enzyme. | 0.403 |
AFUA_3G14100 | AFUA_4G07140 | Q4WYS6 | Q4WNW0 | RNA polymerase II Elongator complex associated protein Kti12, putative. | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | 0.788 |
AFUA_3G14100 | AFUA_5G06140 | Q4WYS6 | Q4WTU6 | RNA polymerase II Elongator complex associated protein Kti12, putative. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.864 |
AFUA_3G14100 | AFUA_5G10470 | Q4WYS6 | Q4WV18 | RNA polymerase II Elongator complex associated protein Kti12, putative. | Riboflavin aldehyde-forming enzyme. | 0.643 |
AFUA_3G14100 | AFUA_5G11130 | Q4WYS6 | Q4WV79 | RNA polymerase II Elongator complex associated protein Kti12, putative. | PAXNEB protein superfamily. | 0.648 |
AFUA_3G14100 | AFUA_6G05090 | Q4WYS6 | Q4WDK8 | RNA polymerase II Elongator complex associated protein Kti12, putative. | RNA polymerase II Elongator subunit, putative. | 0.824 |
AFUA_3G14100 | NCS6 | Q4WYS6 | Q4WJV0 | RNA polymerase II Elongator complex associated protein Kti12, putative. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.599 |
AFUA_3G14100 | uba4 | Q4WYS6 | Q4WV19 | RNA polymerase II Elongator complex associated protein Kti12, putative. | Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.582 |
AFUA_4G07140 | AFUA_3G14100 | Q4WNW0 | Q4WYS6 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | RNA polymerase II Elongator complex associated protein Kti12, putative. | 0.788 |
AFUA_4G07140 | AFUA_5G06140 | Q4WNW0 | Q4WTU6 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | 0.998 |
AFUA_4G07140 | AFUA_5G10470 | Q4WNW0 | Q4WV18 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Riboflavin aldehyde-forming enzyme. | 0.882 |
AFUA_4G07140 | AFUA_5G11130 | Q4WNW0 | Q4WV79 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | PAXNEB protein superfamily. | 0.996 |
AFUA_4G07140 | AFUA_6G05090 | Q4WNW0 | Q4WDK8 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | RNA polymerase II Elongator subunit, putative. | 0.997 |
AFUA_4G07140 | NCS6 | Q4WNW0 | Q4WJV0 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Cytoplasmic tRNA 2-thiolation protein 1; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of tRNA(Lys), tRNA(Glu) and tRNA(Gln). Directly binds tRNAs and probably acts by catalyzing adenylation of tRNAs, an intermediate required for 2-thiolation. It is unclear whether it acts as a sulfurtransferase that transfers sulfur from thiocarboxylated URM1 onto the uridine of tRNAs at wobble position. Prior mcm(5) tRNA modification by the elongator complex is required for 2-thiolation. May also be involved in protein urmylation. | 0.668 |
AFUA_4G07140 | uba4 | Q4WNW0 | Q4WV19 | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | Adenylyltransferase and sulfurtransferase uba4; Plays a central role in 2-thiolation of mcm(5)S(2)U at tRNA wobble positions of cytosolic tRNA(Lys), tRNA(Glu) and tRNA(Gln). Also essential during biosynthesis of the molybdenum cofactor. Acts by mediating the C-terminal thiocarboxylation of sulfur carriers urm1 and mocs2a. Its N-terminus first activates urm1 and mocs2a as acyl- adenylates (-COAMP), then the persulfide sulfur on the catalytic cysteine is transferred to urm1 and mocs2a to form thiocarboxylation (- COSH) of their C-terminus. The reaction probably involves hydrogen sulfide [...] | 0.688 |
AFUA_5G06140 | AFUA_3G09750 | Q4WTU6 | Q4WXJ7 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | rRNA processing protein Utp6, putative. | 0.414 |
AFUA_5G06140 | AFUA_3G14100 | Q4WTU6 | Q4WYS6 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | RNA polymerase II Elongator complex associated protein Kti12, putative. | 0.864 |
AFUA_5G06140 | AFUA_4G07140 | Q4WTU6 | Q4WNW0 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Elongator complex protein 1; Component of the RNA polymerase II elongator complex, a multiprotein complex associated with the RNA polymerase II (Pol II) holoenzyme, and which is involved in transcriptional elongation. Belongs to the ELP1/IKA1 family. | 0.998 |
AFUA_5G06140 | AFUA_5G10470 | Q4WTU6 | Q4WV18 | Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. | Riboflavin aldehyde-forming enzyme. | 0.884 |