STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpD-2Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (341 aa)    
Predicted Functional Partners:
trpE
Anthranilate synthase component I.
 0.999
trpD
Anthranilate synthase component II.
 
 
 0.999
trpC
Indole-3-glycerol-phosphate synthase; Belongs to the TrpC family.
  
 0.999
trpFB
Bifunctional phosphoribosylanthranilate isomerase/tryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpF family.
 
 0.999
trpA
Tryptophan synthase subunit alpha; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
 
  
 0.996
thrA
Bifunctional aspartokinase/homoserine dehydrogenase.
   
  
 0.675
hisI
Bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP diphosphatase protein; In the N-terminal section; belongs to the PRA-CH family.
  
  
 0.660
ung
uracil-DNA glycosylase; Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.
      0.639
hisC
Histidinol-phosphate transaminase; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.
  
  
 0.623
ACY40355.1
Bifunctional putative phospho-2-dehydro-3-deoxyheptonate aldolase/chorismate mutase; aroG/pheA.
  
  
 0.565
Your Current Organism:
Blattabacterium sp. Bge
NCBI taxonomy Id: 331104
Other names: B. sp. (Blattella germanica) str. Bge, Blattabacterium sp. (Blattella germanica) str. Bge
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