STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACY40586.1SPFH domain/band 7 family protein. (313 aa)    
Predicted Functional Partners:
ftsH
AAA-metalloprotease FtsH; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family.
   
 0.960
ACY40583.1
Peptidase M16 family domain-containing protein.
  
 0.906
ACY40584.1
Peptidase M16 family domain-containing protein.
  
 0.906
ACY40550.1
Transmembrane rhomboid family protein.
   
 0.812
ACY40587.1
Hypothetical protein BLBBGE_587.
  
 
 0.810
ACY40585.1
Hypothetical protein BLBBGE_585.
       0.761
dnaK
Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
   
 0.610
ACY40577.1
Hypothetical protein BLBBGE_577.
  
 
 0.576
yidC
Putative inner membrane protein translocase component YidC; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
 
 0.548
nnrE
Carbohydrate kinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
  
  
 0.535
Your Current Organism:
Blattabacterium sp. Bge
NCBI taxonomy Id: 331104
Other names: B. sp. (Blattella germanica) str. Bge, Blattabacterium sp. (Blattella germanica) str. Bge
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.