STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
tRPRTrp operon repressor homolog; This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription. (91 aa)    
Predicted Functional Partners:
tRPB2
Tryptophan synthase beta chain 2; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine.
     
 0.932
tRPD
Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
     
 0.902
tRPF
N-(5'-phosphoribosyl)anthranilate isomerase; Belongs to the TrpF family.
     
 0.873
tRPA
Tryptophan synthase alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family.
     
 0.837
tRPE
Anthranilate synthase component 1.
     
 0.776
tRPC
Indole-3-glycerol phosphate synthase; Belongs to the TrpC family.
     
 0.774
tyrP-A
Tyrosine-specific transport protein.
  
   
 0.761
tyrP-C
Tyrosine-specific transport protein.
  
   
 0.759
CCB88894.1
Glutamine amidotransferase of anthranilate synthase.
     
 0.753
CCB89721.1
Putative uncharacterized protein.
  
   
 0.747
Your Current Organism:
Simkania negevensis
NCBI taxonomy Id: 331113
Other names: S. negevensis Z, Simkania negevensis Z, Simkania negevensis str. Z, Simkania negevensis strain Z
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