STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
NFIA_038700Exopolyphosphatase, putative. (484 aa)    
Predicted Functional Partners:
NFIA_115040
Adenine phosphoribosyltransferase 1.
     
 0.692
NFIA_014080
Endopolyphosphatase; Catalyzes the hydrolysis of inorganic polyphosphate (polyP) chains of many hundreds of phosphate residues into shorter lengths.
    
 
 0.588
NFIA_013340
Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis.
   
  
 0.581
met3
Sulfate adenylyltransferase; Catalyzes the first intracellular reaction of sulfate assimilation, forming adenosine-5'-phosphosulfate (APS) from inorganic sulfate and ATP. Plays an important role in sulfate activation as a component of the biosynthesis pathway of sulfur-containing amino acids. In the C-terminal section; belongs to the APS kinase family.
      
 0.578
NFIA_035970
Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.
  
  
 0.552
NFIA_044540
ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily.
   
  
 0.528
NFIA_m0090
ATP synthase subunit a.
  
  
 0.509
NFIA_014820
Adenylyl-sulfate kinase; Catalyzes the synthesis of activated sulfate.
      
 0.463
NFIA_098080
Methylenetetrahydrofolate dehydrogenase.
  
  
 0.460
NFIA_056380
Ribose 5-phosphate isomerase A.
      
 0.457
Your Current Organism:
Aspergillus fischeri
NCBI taxonomy Id: 331117
Other names: A. fischeri NRRL 181, Aspergillus fischeri NRRL 181, Neosartorya fischeri NRRL 181
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