B0A49_13881 protein (Cryomyces minteri) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

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Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:

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Coexpression

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Score

B0A49_13881

Peroxisomal catalase. (141 aa)

Predicted Functional Partners:

B0A49_10861

0.890

B0A49_01370

0.890

B0A49_04732

0.764

B0A49_11812

0.764

B0A49_04662

0.749

B0A49_11709

0.715

B0A49_04336

0.715

B0A49_03716

0.714

B0A49_03718

0.714

B0A49_10025

0.711

Your Current Organism:

Cryomyces minteri

NCBI taxonomy Id: 331657
Other names: C. minteri, CBS 116302, CBS 116302 (ex-type); CCFEE 5187, CCFEE 5187

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A49_01370	B0A49_03716	A0A4U0XPU2	A0A4U0XAU4	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.947
B0A49_01370	B0A49_03718	A0A4U0XPU2	A0A4U0XCN2	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.947
B0A49_01370	B0A49_04662	A0A4U0XPU2	A0A4U0X1A0	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein.	0.901
B0A49_01370	B0A49_04732	A0A4U0XPU2	A0A4U0X5A3	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Peroxisomal hydratase-dehydrogenase-epimerase.	0.947
B0A49_01370	B0A49_10025	A0A4U0XPU2	A0A4U0WSJ7	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	TPR_REGION domain-containing protein.	0.998
B0A49_01370	B0A49_10861	A0A4U0XPU2	A0A4U0W8J1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.942
B0A49_01370	B0A49_11812	A0A4U0XPU2	A0A4V5NAX1	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Peroxisomal hydratase-dehydrogenase-epimerase.	0.947
B0A49_01370	B0A49_13881	A0A4U0XPU2	A0A4U0USY0	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	Peroxisomal catalase.	0.890
B0A49_03716	B0A49_01370	A0A4U0XAU4	A0A4U0XPU2	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.947
B0A49_03716	B0A49_04662	A0A4U0XAU4	A0A4U0X1A0	Uncharacterized protein.	Uncharacterized protein.	0.880
B0A49_03716	B0A49_10025	A0A4U0XAU4	A0A4U0WSJ7	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.808
B0A49_03716	B0A49_10861	A0A4U0XAU4	A0A4U0W8J1	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.947
B0A49_03716	B0A49_13881	A0A4U0XAU4	A0A4U0USY0	Uncharacterized protein.	Peroxisomal catalase.	0.714
B0A49_03718	B0A49_01370	A0A4U0XCN2	A0A4U0XPU2	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.947
B0A49_03718	B0A49_04662	A0A4U0XCN2	A0A4U0X1A0	Uncharacterized protein.	Uncharacterized protein.	0.880
B0A49_03718	B0A49_10025	A0A4U0XCN2	A0A4U0WSJ7	Uncharacterized protein.	TPR_REGION domain-containing protein.	0.808
B0A49_03718	B0A49_10861	A0A4U0XCN2	A0A4U0W8J1	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.947
B0A49_03718	B0A49_13881	A0A4U0XCN2	A0A4U0USY0	Uncharacterized protein.	Peroxisomal catalase.	0.714
B0A49_04336	B0A49_13881	A0A4U0WXJ0	A0A4U0USY0	Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family.	Peroxisomal catalase.	0.715
B0A49_04662	B0A49_01370	A0A4U0X1A0	A0A4U0XPU2	Uncharacterized protein.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.901

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Network Stats

number of nodes:

11

number of edges:

29

average node degree:

5.27

avg. local clustering coefficient:

0.856

expected number of edges:

18

PPI enrichment p-value:

0.0139

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0032508

DNA duplex unwinding

4 of 51

2.01

1.8

0.00026

GO:0000723

Telomere maintenance

3 of 36

2.04

1.42

0.0018

GO:0070199

Establishment of protein localization to chromosome

2 of 6

2.64

1.35

0.0035

GO:0007004

Telomere maintenance via telomerase

2 of 5

2.72

1.35

0.0035

GO:2000573

Positive regulation of DNA biosynthetic process

2 of 9

2.47

1.25

0.0051

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0043047

Single-stranded telomeric DNA binding

2 of 4

2.82

1.21

0.0063

GO:0140097

Catalytic activity, acting on DNA

4 of 151

1.54

1.02

0.0063

GO:0009982

Pseudouridine synthase activity

2 of 10

2.42

1.01

0.0139

GO:0008094

ATP-dependent activity, acting on DNA

3 of 88

1.65

0.91

0.0139

GO:0004520

Endodeoxyribonuclease activity

2 of 21

2.1

0.88

0.0227

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030870

Mre11 complex

2 of 2

3.12

1.41

0.0029

GO:0005694

Chromosome

5 of 360

1.26

0.97

0.0029

GO:0005657

Replication fork

2 of 27

1.99

0.82

0.0280

GO:0043232

Intracellular non-membrane-bounded organelle

7 of 1612

0.76

0.5

0.0145

GO:0070013

Intracellular organelle lumen

5 of 993

0.82

0.46

0.0427

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:5386

Homologous DNA Pairing and Strand Exchange, and Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)

3 of 20

2.3

1.89

0.00026

CL:5382

HDR through Homologous Recombination (HRR) or Single Strand Annealing (SSA), and DNA polymerase complex

4 of 60

1.94

1.81

0.00021

CL:5399

Sensing of DNA Double Strand Breaks, and D-loop DNA binding

2 of 5

2.72

1.48

0.0020

CL:7848

Box H/ACA RNP complex, and Box H/ACA snoRNP assembly

2 of 6

2.64

1.42

0.0025

CL:4172

Protein palmitoylation, and Telomere assembly

2 of 11

2.38

1.19

0.0063

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map03450

Non-homologous end-joining

2 of 12

2.34

1.16

0.0072

map03440

Homologous recombination

2 of 54

1.69

0.67

0.0496

map03030

DNA replication

2 of 49

1.73

0.67

0.0496

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-5685938

HDR through Single Strand Annealing (SSA)

4 of 26

2.31

2.7

5.73e-06

MAP-180786

Extension of Telomeres

4 of 28

2.28

2.68

5.73e-06

MAP-157579

Telomere Maintenance

4 of 35

2.18

2.63

5.73e-06

MAP-5693607

Processing of DNA double-strand break ends

4 of 36

2.17

2.62

5.73e-06

MAP-5685942

HDR through Homologous Recombination (HRR)

4 of 39

2.13

2.6

5.73e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0030870

Mre11 complex

2 of 5

2.72

1.09

0.0106

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