STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0A49_09395Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (624 aa)    
Predicted Functional Partners:
B0A49_05403
Replication factor C subunit 2.
  
 0.997
FEN1
Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...]
   
 0.996
B0A49_07342
Uncharacterized protein.
   
 0.995
B0A49_06225
UmuC domain-containing protein.
   
 0.995
B0A49_00396
Replication factor C subunit 5.
  
 0.995
B0A49_04253
DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR).
   
 0.991
B0A49_04104
AAA domain-containing protein.
  
 0.989
B0A49_05649
Ubiquitin-like domain-containing protein.
   
 0.988
B0A49_00077
WD_REPEATS_REGION domain-containing protein.
   
 0.984
B0A49_02585
UmuC domain-containing protein.
   
 0.981
Your Current Organism:
Cryomyces minteri
NCBI taxonomy Id: 331657
Other names: C. minteri, CBS 116302, CBS 116302 (ex-type); CCFEE 5187, CCFEE 5187
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.