B0A49_12544 protein (Cryomyces minteri) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

B0A49_12544

Polyketide_cyc domain-containing protein. (662 aa)

Predicted Functional Partners:

B0A49_04861

0.840

B0A49_03970

0.840

B0A49_08067

0.822

B0A49_11895

0.640

B0A49_02214

0.640

B0A49_08118

0.640

B0A49_10915

0.626

B0A49_08138

0.626

B0A49_02938

0.626

B0A49_05040

0.626

Your Current Organism:

Cryomyces minteri

NCBI taxonomy Id: 331657
Other names: C. minteri, CBS 116302, CBS 116302 (ex-type); CCFEE 5187, CCFEE 5187

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A49_02214	B0A49_08067	A0A4U0WCS0	A0A4U0WQI4	Lactamase_B domain-containing protein.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.625
B0A49_02214	B0A49_12544	A0A4U0WCS0	A0A4U0WAR2	Lactamase_B domain-containing protein.	Polyketide_cyc domain-containing protein.	0.640
B0A49_02938	B0A49_08067	A0A4U0XG64	A0A4U0WQI4	Lactamase_B domain-containing protein.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.600
B0A49_02938	B0A49_12544	A0A4U0XG64	A0A4U0WAR2	Lactamase_B domain-containing protein.	Polyketide_cyc domain-containing protein.	0.626
B0A49_03970	B0A49_08067	A0A4U0XBL7	A0A4U0WQI4	PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.997
B0A49_03970	B0A49_12544	A0A4U0XBL7	A0A4U0WAR2	PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Polyketide_cyc domain-containing protein.	0.840
B0A49_04861	B0A49_08067	A0A4U0X5I5	A0A4U0WQI4	PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.997
B0A49_04861	B0A49_12544	A0A4U0X5I5	A0A4U0WAR2	PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	Polyketide_cyc domain-containing protein.	0.840
B0A49_05040	B0A49_08067	A0A4U0XH31	A0A4U0WQI4	Lactamase_B domain-containing protein.	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	0.625
B0A49_05040	B0A49_12544	A0A4U0XH31	A0A4U0WAR2	Lactamase_B domain-containing protein.	Polyketide_cyc domain-containing protein.	0.626
B0A49_08067	B0A49_02214	A0A4U0WQI4	A0A4U0WCS0	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Lactamase_B domain-containing protein.	0.625
B0A49_08067	B0A49_02938	A0A4U0WQI4	A0A4U0XG64	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Lactamase_B domain-containing protein.	0.600
B0A49_08067	B0A49_03970	A0A4U0WQI4	A0A4U0XBL7	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.997
B0A49_08067	B0A49_04861	A0A4U0WQI4	A0A4U0X5I5	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	PKS_KS domain-containing protein; Belongs to the thiolase-like superfamily. Beta-ketoacyl-ACP synthases family.	0.997
B0A49_08067	B0A49_05040	A0A4U0WQI4	A0A4U0XH31	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Lactamase_B domain-containing protein.	0.625
B0A49_08067	B0A49_08118	A0A4U0WQI4	A0A4U0WRF4	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Lactamase_B domain-containing protein.	0.625
B0A49_08067	B0A49_08138	A0A4U0WQI4	A0A4U0WJN9	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Lactamase_B domain-containing protein.	0.600
B0A49_08067	B0A49_10915	A0A4U0WQI4	A0A4U0WFA0	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Lactamase_B domain-containing protein.	0.625
B0A49_08067	B0A49_11895	A0A4U0WQI4	A0A4U0VC37	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Lactamase_B domain-containing protein.	0.625
B0A49_08067	B0A49_12544	A0A4U0WQI4	A0A4U0WAR2	Acyl carrier protein; Carrier of the growing fatty acid chain in fatty acid biosynthesis.	Polyketide_cyc domain-containing protein.	0.822

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Network Stats

number of nodes:

11

number of edges:

16

average node degree:

2.91

avg. local clustering coefficient:

0.856

expected number of edges:

13

PPI enrichment p-value:

0.263

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0055085

Transmembrane transport

8 of 394

0.94

0.88

0.00013

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0022857

Transmembrane transporter activity

9 of 389

0.99

1.06

6.57e-06

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0016020

Membrane

10 of 1216

0.55

0.43

0.0014

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:4476

beta-Lactam resistance, and AcrB/AcrD/AcrF family

9 of 45

1.93

4.85

9.32e-14

CL:4552

Mixed, incl. Protein of unknown function (DUF2892), and Protein export membrane protein

5 of 5

2.63

4.73

8.65e-10

CL:4474

Mixed, incl. beta-Lactam resistance, and MacB-like periplasmic core domain

10 of 110

1.59

3.37

4.31e-13

CL:4478

beta-Lactam resistance

4 of 24

1.85

2.04

4.03e-05

CL:4479

Acriflavin resistance protein, and Biotin-lipoyl like

3 of 18

1.85

1.44

0.0012

(more ...)

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01503

Cationic antimicrobial peptide (CAMP) resistance

7 of 77

1.59

2.62

1.65e-08

map01501

beta-Lactam resistance

7 of 85

1.55

2.52

1.65e-08

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:1902495

Transmembrane transporter complex

5 of 56

1.58

1.78

4.05e-05

GOCC:1990281

Efflux pump complex

2 of 12

1.85

0.89

0.0191

GOCC:0016020

Membrane

9 of 788

0.69

0.58

0.00044

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0175

Coiled coil

6 of 445

0.76

0.42

0.0470

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13437

HlyD family secretion protein

5 of 21

2.01

2.8

1.02e-06

PF13533

Biotin-lipoyl like

4 of 13

2.12

2.44

1.24e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR006143

RND efflux pump, membrane fusion protein

4 of 15

2.06

2.0

9.86e-05

IPR032317

RND efflux pump, membrane fusion protein, barrel-sandwich domain

4 of 19

1.95

1.93

0.00011

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