STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
B0A49_04252Folylpolyglutamate synthase; Catalyzes conversion of folates to polyglutamate derivatives allowing concentration of folate compounds in the cell and the intracellular retention of these cofactors, which are important substrates for most of the folate-dependent enzymes that are involved in one-carbon transfer reactions involved in purine, pyrimidine and amino acid synthesis; Belongs to the folylpolyglutamate synthase family. (498 aa)    
Predicted Functional Partners:
B0A49_06948
Pterin-binding domain-containing protein.
 
 
 0.950
B0A49_06730
Pterin-binding domain-containing protein.
 
 
 0.923
B0A49_10773
Flavoprotein domain-containing protein.
     
 0.869
B0A49_08416
Flavoprotein domain-containing protein.
     
 0.869
B0A49_01328
Flavoprotein domain-containing protein.
     
 0.869
B0A49_04368
Thymidylate synthase.
     
 0.859
B0A49_02130
Thymidylate synthase.
     
 0.859
B0A49_03174
Nudix hydrolase domain-containing protein; Belongs to the Nudix hydrolase family.
    
 0.849
B0A49_06858
FSH1 domain-containing protein.
     
 0.845
B0A49_02414
DHFR domain-containing protein; Belongs to the dihydrofolate reductase family.
     
 0.845
Your Current Organism:
Cryomyces minteri
NCBI taxonomy Id: 331657
Other names: C. minteri, CBS 116302, CBS 116302 (ex-type); CCFEE 5187, CCFEE 5187
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