B0A49_04719 protein (Cryomyces minteri) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Cooccurrence

Coexpression

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[Homology]

Score

B0A49_04719

Uncharacterized protein. (1894 aa)

Predicted Functional Partners:

B0A49_09831

0.995

B0A49_02947

0.995

B0A49_03574

0.994

B0A49_01632

0.994

B0A49_08554

0.993

B0A49_04411

0.993

B0A49_08037

0.993

B0A49_13388

0.990

B0A49_07533

0.990

B0A49_07532

0.990

Your Current Organism:

Cryomyces minteri

NCBI taxonomy Id: 331657
Other names: C. minteri, CBS 116302, CBS 116302 (ex-type); CCFEE 5187, CCFEE 5187

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A49_01632	B0A49_02947	A0A4U0XYF6	A0A4U0XIF4	CNH domain-containing protein.	Pep3_Vps18 domain-containing protein.	0.993
B0A49_01632	B0A49_04411	A0A4U0XYF6	A0A4U0X1N0	CNH domain-containing protein.	Vps16_N domain-containing protein.	0.989
B0A49_01632	B0A49_04719	A0A4U0XYF6	A0A4U0XI73	CNH domain-containing protein.	Uncharacterized protein.	0.994
B0A49_01632	B0A49_07532	A0A4U0XYF6	A0A4U0WMM4	CNH domain-containing protein.	Uncharacterized protein.	0.963
B0A49_01632	B0A49_07533	A0A4U0XYF6	A0A4U0WLB5	CNH domain-containing protein.	Uncharacterized protein.	0.963
B0A49_01632	B0A49_08037	A0A4U0XYF6	A0A4V5NCJ3	CNH domain-containing protein.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.989
B0A49_01632	B0A49_08554	A0A4U0XYF6	A0A4U0WQ91	CNH domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.986
B0A49_01632	B0A49_09831	A0A4U0XYF6	A0A4U0WF58	CNH domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.993
B0A49_01632	B0A49_13388	A0A4U0XYF6	A0A4U0VF94	CNH domain-containing protein.	Uncharacterized protein.	0.963
B0A49_02947	B0A49_01632	A0A4U0XIF4	A0A4U0XYF6	Pep3_Vps18 domain-containing protein.	CNH domain-containing protein.	0.993
B0A49_02947	B0A49_03574	A0A4U0XIF4	A0A4U0XS76	Pep3_Vps18 domain-containing protein.	CNH domain-containing protein.	0.993
B0A49_02947	B0A49_04411	A0A4U0XIF4	A0A4U0X1N0	Pep3_Vps18 domain-containing protein.	Vps16_N domain-containing protein.	0.994
B0A49_02947	B0A49_04719	A0A4U0XIF4	A0A4U0XI73	Pep3_Vps18 domain-containing protein.	Uncharacterized protein.	0.995
B0A49_02947	B0A49_07532	A0A4U0XIF4	A0A4U0WMM4	Pep3_Vps18 domain-containing protein.	Uncharacterized protein.	0.989
B0A49_02947	B0A49_07533	A0A4U0XIF4	A0A4U0WLB5	Pep3_Vps18 domain-containing protein.	Uncharacterized protein.	0.989
B0A49_02947	B0A49_08037	A0A4U0XIF4	A0A4V5NCJ3	Pep3_Vps18 domain-containing protein.	Probable vacuolar protein sorting-associated protein 16 homolog; Essential for vacuolar protein sorting. Required for vacuole biogenesis, stability and to maintain vacuole morphology.	0.994
B0A49_02947	B0A49_08554	A0A4U0XIF4	A0A4U0WQ91	Pep3_Vps18 domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.994
B0A49_02947	B0A49_09831	A0A4U0XIF4	A0A4U0WF58	Pep3_Vps18 domain-containing protein.	Uncharacterized protein; Belongs to the STXBP/unc-18/SEC1 family.	0.996
B0A49_02947	B0A49_13388	A0A4U0XIF4	A0A4U0VF94	Pep3_Vps18 domain-containing protein.	Uncharacterized protein.	0.989
B0A49_03574	B0A49_02947	A0A4U0XS76	A0A4U0XIF4	CNH domain-containing protein.	Pep3_Vps18 domain-containing protein.	0.993

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Network Stats

number of nodes:

11

number of edges:

40

average node degree:

7.27

avg. local clustering coefficient:

0.903

expected number of edges:

10

PPI enrichment p-value:

1.06e-12

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006744

Ubiquinone biosynthetic process

10 of 17

2.31

7.86

6.69e-19

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0008425

2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity

3 of 4

2.42

1.78

0.00047

GO:0016705

Oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen

4 of 27

1.71

1.53

0.00047

GO:0071949

FAD binding

3 of 15

1.84

1.32

0.0022

GO:0102208

2-polyprenyl-6-hydroxyphenol methylase activity

2 of 3

2.37

1.09

0.0097

GO:0008689

3-demethylubiquinone-9 3-O-methyltransferase activity

2 of 3

2.37

1.09

0.0097

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0110142

Ubiquinone biosynthesis complex

4 of 5

2.45

3.23

6.24e-07

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3314

Ubiquinone metabolic process

9 of 14

2.35

7.29

7.38e-17

CL:3316

Ubiquinone biosynthesis complex, and Ubiquinone biosynthesis O-methyltransferase

7 of 7

2.54

6.55

6.37e-14

CL:3309

Mixed, incl. Ubiquinone metabolic process, and Translocase

10 of 50

1.84

4.9

1.17e-15

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

amg00130

Ubiquinone and other terpenoid-quinone biosynthesis

8 of 14

2.3

6.47

4.82e-15

amg01110

Biosynthesis of secondary metabolites

8 of 289

0.99

1.04

8.45e-06

amg01100

Metabolic pathways

8 of 650

0.63

0.49

0.0026

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0110142

Ubiquinone biosynthesis complex

6 of 14

2.18

4.16

1.27e-09

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0830

Ubiquinone

8 of 15

2.27

6.2

1.56e-14

KW-0831

Ubiquinone biosynthesis

5 of 7

2.4

4.14

5.99e-09

KW-0949

S-adenosyl-L-methionine

3 of 59

1.25

0.6

0.0465

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF13489

Methyltransferase domain

3 of 8

2.12

1.45

0.0017

PF08491

Squalene epoxidase

2 of 2

2.54

1.03

0.0134

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR010971

Ubiquinone biosynthesis hydroxylase UbiH/COQ6

3 of 3

2.54

1.77

0.00053

IPR002938

FAD-binding domain

3 of 4

2.42

1.76

0.00053

IPR018168

Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6, conserved site

2 of 2

2.54

0.9

0.0227

IPR010233

Ubiquinone biosynthesis O-methyltransferase

2 of 2

2.54

0.9

0.0227

IPR036188

FAD/NAD(P)-binding domain superfamily

3 of 34

1.49

0.68

0.0392

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