B0A49_03504 protein (Cryomyces minteri) - STRING interaction network

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

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Score

B0A49_03504

Beta-lactamase domain-containing protein. (407 aa)

Predicted Functional Partners:

B0A49_06176

0.862

B0A49_04103

0.644

B0A49_01431

0.638

B0A49_01179

0.632

B0A49_11769

0.604

B0A49_10112

0.604

B0A49_05887

0.604

B0A49_04776

0.592

B0A49_01211

0.592

B0A49_07095

0.566

Your Current Organism:

Cryomyces minteri

NCBI taxonomy Id: 331657
Other names: C. minteri, CBS 116302, CBS 116302 (ex-type); CCFEE 5187, CCFEE 5187

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A49_01179	B0A49_01431	A0A4U0XI10	A0A4U0XRH5	PALP domain-containing protein.	Uncharacterized protein.	0.846
B0A49_01179	B0A49_03504	A0A4U0XI10	A0A4U0XLU4	PALP domain-containing protein.	Beta-lactamase domain-containing protein.	0.632
B0A49_01179	B0A49_04103	A0A4U0XI10	A0A4U0XDM3	PALP domain-containing protein.	Uncharacterized protein.	0.879
B0A49_01179	B0A49_05887	A0A4U0XI10	A0A4V5NCR7	PALP domain-containing protein.	Uncharacterized protein.	0.776
B0A49_01179	B0A49_06176	A0A4U0XI10	A0A4U0WM62	PALP domain-containing protein.	Tryptophan synthase.	0.933
B0A49_01179	B0A49_10112	A0A4U0XI10	A0A4U0WUM1	PALP domain-containing protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.789
B0A49_01179	B0A49_11769	A0A4U0XI10	A0A4U0WAW3	PALP domain-containing protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.789
B0A49_01211	B0A49_01431	A0A4U0XNV9	A0A4U0XRH5	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family.	Uncharacterized protein.	0.453
B0A49_01211	B0A49_03504	A0A4U0XNV9	A0A4U0XLU4	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family.	Beta-lactamase domain-containing protein.	0.592
B0A49_01211	B0A49_04103	A0A4U0XNV9	A0A4U0XDM3	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family.	Uncharacterized protein.	0.406
B0A49_01211	B0A49_06176	A0A4U0XNV9	A0A4U0WM62	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family.	Tryptophan synthase.	0.818
B0A49_01431	B0A49_01179	A0A4U0XRH5	A0A4U0XI10	Uncharacterized protein.	PALP domain-containing protein.	0.846
B0A49_01431	B0A49_01211	A0A4U0XRH5	A0A4U0XNV9	Uncharacterized protein.	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family.	0.453
B0A49_01431	B0A49_03504	A0A4U0XRH5	A0A4U0XLU4	Uncharacterized protein.	Beta-lactamase domain-containing protein.	0.638
B0A49_01431	B0A49_04103	A0A4U0XRH5	A0A4U0XDM3	Uncharacterized protein.	Uncharacterized protein.	0.892
B0A49_01431	B0A49_04776	A0A4U0XRH5	A0A4U0WTT8	Uncharacterized protein.	Prephenate dehydrogenase [NADP(+)]; Belongs to the prephenate/arogenate dehydrogenase family.	0.453
B0A49_01431	B0A49_05887	A0A4U0XRH5	A0A4V5NCR7	Uncharacterized protein.	Uncharacterized protein.	0.843
B0A49_01431	B0A49_06176	A0A4U0XRH5	A0A4U0WM62	Uncharacterized protein.	Tryptophan synthase.	0.919
B0A49_01431	B0A49_10112	A0A4U0XRH5	A0A4U0WUM1	Uncharacterized protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.852
B0A49_01431	B0A49_11769	A0A4U0XRH5	A0A4U0WAW3	Uncharacterized protein.	Cystathionine beta-synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family.	0.852

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Network Stats

number of nodes:

11

number of edges:

13

average node degree:

2.36

avg. local clustering coefficient:

0.915

expected number of edges:

10

PPI enrichment p-value:

0.226

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000160

Phosphorelay signal transduction system

8 of 49

1.7

3.19

7.31e-10

GO:0050794

Regulation of cellular process

9 of 314

0.94

1.0

4.62e-06

GO:0031323

Regulation of cellular metabolic process

8 of 262

0.97

0.99

2.26e-05

GO:0006355

Regulation of transcription, DNA-templated

7 of 229

0.97

0.91

0.00017

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003677

DNA binding

7 of 372

0.76

0.46

0.0301

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3421

Two-component regulatory system, and Sporulation and spore germination

9 of 19

2.16

6.18

1.81e-15

CL:3423

Two-component regulatory system, and Sporulation and spore germination

8 of 13

2.28

6.18

2.00e-14

CL:3316

Mixed, incl. Intracellular signal transduction, and Phosphate ion transport

10 of 132

1.37

2.38

2.01e-11

CL:3426

Two-component regulatory system

2 of 5

2.09

0.89

0.0220

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0902

Two-component regulatory system

7 of 15

2.16

4.89

1.07e-11

KW-0597

Phosphoprotein

6 of 28

1.82

3.06

2.79e-08

KW-0805

Transcription regulation

6 of 122

1.18

1.24

4.98e-05

KW-0238

DNA-binding

7 of 170

1.1

1.19

1.69e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR001867

OmpR/PhoB-type DNA-binding domain

7 of 10

2.33

5.29

8.42e-12

IPR039420

Transcriptional regulatory protein WalR-like

7 of 21

2.01

4.1

2.53e-10

IPR011006

CheY-like superfamily

6 of 23

1.9

3.15

4.55e-08

IPR001789

Signal transduction response regulator, receiver domain

6 of 23

1.9

3.15

4.55e-08

IPR016032

Signal transduction response regulator, C-terminal effector

4 of 25

1.69

1.59

0.00031

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00862

Transcriptional regulatory protein, C terminal

7 of 10

2.33

5.72

7.18e-13

SM00448

cheY-homologous receiver domain

6 of 23

1.9

3.44

5.82e-09

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