B0A49_01185 protein (Cryomyces minteri) - STRING interaction network

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:

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Score

B0A49_01185

BZIP domain-containing protein. (256 aa)

Predicted Functional Partners:

B0A49_09575

0.997

B0A49_08053

0.997

B0A49_09174

0.997

B0A49_01210

0.997

B0A49_06107

0.997

B0A49_08717

0.997

B0A49_04758

0.997

B0A49_05255

0.997

B0A49_03661

0.997

B0A49_04061

0.997

Your Current Organism:

Cryomyces minteri

NCBI taxonomy Id: 331657
Other names: C. minteri, CBS 116302, CBS 116302 (ex-type); CCFEE 5187, CCFEE 5187

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A49_01185	B0A49_01210	A0A4U0XWX8	A0A4U0WSW2	BZIP domain-containing protein.	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	0.997
B0A49_01185	B0A49_03661	A0A4U0XWX8	A0A4U0XCT8	BZIP domain-containing protein.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.997
B0A49_01185	B0A49_04061	A0A4U0XWX8	A0A4U0XGG3	BZIP domain-containing protein.	60S ribosomal protein L33-A.	0.997
B0A49_01185	B0A49_04758	A0A4U0XWX8	A0A4U0X1X3	BZIP domain-containing protein.	60S ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family.	0.997
B0A49_01185	B0A49_05255	A0A4U0XWX8	A0A4U0XB44	BZIP domain-containing protein.	40S ribosomal protein S20.	0.997
B0A49_01185	B0A49_06107	A0A4U0XWX8	A0A4U0WU00	BZIP domain-containing protein.	40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.	0.997
B0A49_01185	B0A49_08053	A0A4U0XWX8	A0A4U0WJJ3	BZIP domain-containing protein.	60S ribosomal protein L25.	0.997
B0A49_01185	B0A49_08717	A0A4U0XWX8	A0A4U0WXM6	BZIP domain-containing protein.	40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.997
B0A49_01185	B0A49_09174	A0A4U0XWX8	A0A4U0WJP5	BZIP domain-containing protein.	60S ribosomal protein L7.	0.997
B0A49_01185	B0A49_09575	A0A4U0XWX8	A0A4U0WF35	BZIP domain-containing protein.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.997
B0A49_01210	B0A49_01185	A0A4U0WSW2	A0A4U0XWX8	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	BZIP domain-containing protein.	0.997
B0A49_01210	B0A49_03661	A0A4U0WSW2	A0A4U0XCT8	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	40S ribosomal protein S25; Belongs to the eukaryotic ribosomal protein eS25 family.	0.999
B0A49_01210	B0A49_04061	A0A4U0WSW2	A0A4U0XGG3	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	60S ribosomal protein L33-A.	0.998
B0A49_01210	B0A49_04758	A0A4U0WSW2	A0A4U0X1X3	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	60S ribosomal protein L27a; Belongs to the universal ribosomal protein uL15 family.	0.998
B0A49_01210	B0A49_05255	A0A4U0WSW2	A0A4U0XB44	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	40S ribosomal protein S20.	0.999
B0A49_01210	B0A49_06107	A0A4U0WSW2	A0A4U0WU00	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	40S ribosomal protein S13; Belongs to the universal ribosomal protein uS15 family.	0.999
B0A49_01210	B0A49_08053	A0A4U0WSW2	A0A4U0WJJ3	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	60S ribosomal protein L25.	0.998
B0A49_01210	B0A49_08717	A0A4U0WSW2	A0A4U0WXM6	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	40S ribosomal protein S2; Belongs to the universal ribosomal protein uS5 family.	0.999
B0A49_01210	B0A49_09174	A0A4U0WSW2	A0A4U0WJP5	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	60S ribosomal protein L7.	0.998
B0A49_01210	B0A49_09575	A0A4U0WSW2	A0A4U0WF35	40S ribosomal protein S14; Belongs to the universal ribosomal protein uS11 family.	40S ribosomal protein S6; Belongs to the eukaryotic ribosomal protein eS6 family.	0.999

page 1 of 6

Network Stats

number of nodes:

11

number of edges:

20

average node degree:

3.64

avg. local clustering coefficient:

0.778

expected number of edges:

10

PPI enrichment p-value:

0.00429

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006636

Unsaturated fatty acid biosynthetic process

6 of 6

3.38

7.92

3.36e-15

GO:0045471

Response to ethanol

4 of 5

3.28

4.85

1.49e-09

GO:0000001

Mitochondrion inheritance

4 of 15

2.8

4.12

2.11e-08

GO:0022900

Electron transport chain

5 of 63

2.28

3.83

1.64e-08

GO:0046394

Carboxylic acid biosynthetic process

7 of 243

1.84

3.47

1.49e-09

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0004768

stearoyl-CoA 9-desaturase activity

6 of 6

3.38

8.1

1.56e-15

GO:0016491

Oxidoreductase activity

8 of 1513

1.1

1.24

5.81e-06

GO:0046872

Metal ion binding

7 of 2049

0.91

0.75

0.0011

GO:0003824

Catalytic activity

11 of 6776

0.59

0.51

9.37e-05

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0030176

Integral component of endoplasmic reticulum membrane

4 of 69

2.14

2.43

1.43e-05

GO:0005789

Endoplasmic reticulum membrane

6 of 546

1.42

1.69

1.43e-05

GO:0031090

Organelle membrane

7 of 1452

1.06

1.09

4.35e-05

GO:0016021

Integral component of membrane

7 of 2084

0.9

0.8

0.00036

GO:0043231

Intracellular membrane-bounded organelle

10 of 6693

0.55

0.46

0.00052

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:19204

Fatty acid metabolism, and Very long-chain fatty acid biosynthetic process

6 of 11

3.12

7.27

3.39e-14

CL:19208

Acyl-CoA desaturase

4 of 5

3.28

5.05

6.33e-10

CL:17721

2-deoxyribonucleotide biosynthetic process, and Serine hydrolase FSH

3 of 10

2.86

2.99

3.27e-06

CL:17722

Thymidylate synthase activity, and Dihydrofolate metabolic process

2 of 5

2.98

1.8

0.00054

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map01040

Biosynthesis of unsaturated fatty acids

6 of 100

2.16

4.39

2.56e-10

map01212

Fatty acid metabolism

6 of 136

2.02

3.97

7.62e-10

map00670

One carbon pool by folate

3 of 21

2.53

2.86

4.16e-06

map00790

Folate biosynthesis

3 of 109

1.82

1.64

0.00037

map01100

Metabolic pathways

11 of 4354

0.78

0.81

1.31e-07

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-75105

Fatty acyl-CoA biosynthesis

6 of 63

2.36

4.86

1.13e-10

MAP-8978868

Fatty acid metabolism

6 of 264

1.74

2.64

2.33e-07

MAP-196757

Metabolism of folate and pterines

3 of 32

2.35

2.19

6.73e-05

MAP-556833

Metabolism of lipids

6 of 747

1.28

1.38

5.24e-05

MAP-196849

Metabolism of water-soluble vitamins and cofactors

3 of 134

1.73

1.19

0.0035

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005783

Endoplasmic reticulum

6 of 367

1.59

2.09

3.48e-06

GOCC:0043231

Intracellular membrane-bounded organelle

8 of 4252

0.65

0.45

0.0125

GOCC:0005737

Cytoplasm

8 of 4349

0.64

0.44

0.0125

GOCC:0005622

Intracellular

11 of 9506

0.44

0.35

0.0047

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0275

Fatty acid biosynthesis

6 of 11

3.12

7.82

3.00e-15

KW-0249

Electron transport

6 of 19

2.88

7.29

1.43e-14

KW-0349

Heme

6 of 175

1.91

3.62

1.76e-09

KW-0560

Oxidoreductase

6 of 392

1.56

2.37

1.34e-07

KW-1133

Transmembrane helix

6 of 3683

0.59

0.36

0.0407

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00487

Fatty acid desaturase

4 of 13

2.87

3.92

5.53e-08

PF03959

Serine hydrolase (FSH1)

2 of 6

2.9

1.39

0.0031

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR015876

Acyl-CoA desaturase

6 of 6

3.38

7.91

3.45e-15

IPR009160

Acyl-CoA desaturase, haem/steroid binding domain-containing

6 of 6

3.38

7.91

3.45e-15

IPR036400

Cytochrome b5-like heme/steroid binding domain superfamily

6 of 25

2.76

6.29

9.12e-13

IPR001199

Cytochrome b5-like heme/steroid binding domain

6 of 25

2.76

6.29

9.12e-13

IPR018506

Cytochrome b5, heme-binding site

5 of 14

2.93

5.59

3.80e-11

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM01117

Cytochrome b5-like Heme/Steroid binding domain

5 of 25

2.68

5.04

2.34e-10

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