B0A49_00017 protein (Cryomyces minteri) - STRING interaction network

Nodes:

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second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

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[Homology]

Score

B0A49_00017

Uncharacterized protein. (337 aa)

Predicted Functional Partners:

B0A49_00236

0.877

B0A49_09136

0.779

B0A49_01193

0.778

B0A49_02208

0.774

B0A49_06176

0.771

B0A49_03042

0.767

B0A49_11468

0.764

B0A49_01048

0.722

B0A49_09965

0.699

B0A49_04346

0.699

Your Current Organism:

Cryomyces minteri

NCBI taxonomy Id: 331657
Other names: C. minteri, CBS 116302, CBS 116302 (ex-type); CCFEE 5187, CCFEE 5187

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A49_00017	B0A49_00236	A0A4U0Y232	A0A4U0Y1Z3	Uncharacterized protein.	Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.877
B0A49_00017	B0A49_01048	A0A4U0Y232	A0A4U0XYD7	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.722
B0A49_00017	B0A49_01193	A0A4U0Y232	A0A4U0XVC7	Uncharacterized protein.	Uncharacterized protein.	0.778
B0A49_00017	B0A49_02208	A0A4U0Y232	A0A4U0XG97	Uncharacterized protein.	Uncharacterized protein.	0.774
B0A49_00017	B0A49_03042	A0A4U0Y232	A0A4V5NGT2	Uncharacterized protein.	ANAPC5 domain-containing protein.	0.767
B0A49_00017	B0A49_04346	A0A4U0Y232	A0A4U0XPP0	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.699
B0A49_00017	B0A49_06176	A0A4U0Y232	A0A4U0WM62	Uncharacterized protein.	Tryptophan synthase.	0.771
B0A49_00017	B0A49_09136	A0A4U0Y232	A0A4U0W8W7	Uncharacterized protein.	DOC domain-containing protein.	0.779
B0A49_00017	B0A49_09965	A0A4U0Y232	A0A4U0WM14	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.699
B0A49_00017	B0A49_11468	A0A4U0Y232	A0A4U0WIQ6	Uncharacterized protein.	Uncharacterized protein.	0.764
B0A49_00236	B0A49_00017	A0A4U0Y1Z3	A0A4U0Y232	Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.877
B0A49_00236	B0A49_01048	A0A4U0Y1Z3	A0A4U0XYD7	Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.834
B0A49_01048	B0A49_00017	A0A4U0XYD7	A0A4U0Y232	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Uncharacterized protein.	0.722
B0A49_01048	B0A49_00236	A0A4U0XYD7	A0A4U0Y1Z3	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	Kinesin heavy chain; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.834
B0A49_01193	B0A49_00017	A0A4U0XVC7	A0A4U0Y232	Uncharacterized protein.	Uncharacterized protein.	0.778
B0A49_02208	B0A49_00017	A0A4U0XG97	A0A4U0Y232	Uncharacterized protein.	Uncharacterized protein.	0.774
B0A49_02208	B0A49_03042	A0A4U0XG97	A0A4V5NGT2	Uncharacterized protein.	ANAPC5 domain-containing protein.	0.998
B0A49_02208	B0A49_04346	A0A4U0XG97	A0A4U0XPP0	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.993
B0A49_02208	B0A49_09136	A0A4U0XG97	A0A4U0W8W7	Uncharacterized protein.	DOC domain-containing protein.	0.998
B0A49_02208	B0A49_09965	A0A4U0XG97	A0A4U0WM14	Uncharacterized protein.	CULLIN_2 domain-containing protein; Belongs to the cullin family.	0.993

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Network Stats

number of nodes:

11

number of edges:

21

average node degree:

3.82

avg. local clustering coefficient:

0.828

expected number of edges:

12

PPI enrichment p-value:

0.011

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006526

Arginine biosynthetic process

9 of 27

2.54

8.65

7.06e-19

GO:0042450

Arginine biosynthetic process via ornithine

4 of 5

2.92

4.46

5.70e-09

GO:1901566

Organonitrogen compound biosynthetic process

10 of 655

1.2

1.78

4.93e-10

GO:0044249

Cellular biosynthetic process

10 of 1175

0.95

1.09

9.59e-08

GO:0016310

Phosphorylation

4 of 406

1.01

0.6

0.0224

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003991

Acetylglutamate kinase activity

4 of 4

3.02

4.14

2.53e-08

GO:0003942

N-acetyl-gamma-glutamyl-phosphate reductase activity

4 of 4

3.02

4.14

2.53e-08

GO:0051287

NAD binding

4 of 51

1.91

2.27

1.34e-05

GO:0046983

Protein dimerization activity

4 of 61

1.83

2.11

2.38e-05

GO:0036094

Small molecule binding

10 of 1122

0.97

1.11

1.68e-07

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0005737

Cytoplasm

10 of 2580

0.61

0.5

0.00040

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3509

Arginine biosynthesis, and Lysine biosynthesis

11 of 18

2.8

12.87

6.64e-27

CL:3510

Arginine biosynthesis

6 of 13

2.68

6.08

1.70e-12

CL:3535

Lysine biosynthesis, and ATP-grasp domain

5 of 5

3.02

5.72

2.52e-11

CL:3512

Arginine biosynthesis

2 of 8

2.42

1.06

0.0115

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00220

Arginine biosynthesis

9 of 46

2.31

7.66

2.40e-18

map01210

2-Oxocarboxylic acid metabolism

10 of 86

2.08

6.71

1.49e-18

map01230

Biosynthesis of amino acids

10 of 248

1.62

3.72

1.31e-14

map00300

Lysine biosynthesis

2 of 36

1.76

0.96

0.0125

map01110

Biosynthesis of secondary metabolites

9 of 1188

0.9

0.94

2.11e-06

(more ...)

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0005739

Mitochondrion

8 of 79

2.02

4.99

4.30e-13

GOCC:0005737

Cytoplasm

10 of 2107

0.69

0.63

2.32e-05

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0055

Arginine biosynthesis

6 of 13

2.68

6.37

4.18e-13

KW-0028

Amino-acid biosynthesis

9 of 71

2.12

6.26

2.83e-16

KW-0457

Lysine biosynthesis

3 of 5

2.8

3.15

1.55e-06

KW-0963

Cytoplasm

9 of 264

1.55

3.06

8.02e-12

KW-0521

NADP

4 of 28

2.17

2.99

8.58e-07

(more ...)

Protein Domains (Pfam)

domain

description

count in network

strength

signal

false discovery rate

PF00696

Amino acid kinase family

4 of 9

2.67

3.48

3.06e-07

PF02774

Semialdehyde dehydrogenase, dimerisation domain

3 of 4

2.89

2.72

1.08e-05

Protein Domains and Features (InterPro)

domain

description

count in network

strength

signal

false discovery rate

IPR004662

Acetylglutamate kinase family

4 of 4

3.02

3.89

7.60e-08

IPR000706

N-acetyl-gamma-glutamyl-phosphate reductase, type 1

4 of 4

3.02

3.89

7.60e-08

IPR000534

Semialdehyde dehydrogenase, NAD-binding

4 of 5

2.92

3.87

7.60e-08

IPR036393

Acetylglutamate kinase-like superfamily

4 of 9

2.67

3.58

1.94e-07

IPR001048

Aspartate/glutamate/uridylate kinase

4 of 9

2.67

3.58

1.94e-07

(more ...)

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00859

Semialdehyde dehydrogenase, NAD binding domain

4 of 5

2.92

4.29

1.21e-08

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