B0A49_06264 protein (Cryomyces minteri) - STRING interaction network

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second shell of interactors

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a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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Score

B0A49_06264

DAO domain-containing protein. (347 aa)

Predicted Functional Partners:

B0A49_02681

0.896

B0A49_09012

0.849

B0A49_10319

0.839

B0A49_05004

0.839

B0A49_03885

0.834

B0A49_13992

0.830

B0A49_12508

0.830

B0A49_11082

0.830

B0A49_02026

0.826

B0A49_02025

0.826

Your Current Organism:

Cryomyces minteri

NCBI taxonomy Id: 331657
Other names: C. minteri, CBS 116302, CBS 116302 (ex-type); CCFEE 5187, CCFEE 5187

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A49_02025	B0A49_02026	A0A4U0XEC9	A0A4U0XE05	Uncharacterized protein.	Putative ATP-citrate synthase subunit 1.	0.929
B0A49_02025	B0A49_03885	A0A4U0XEC9	A0A4U0XBB5	Uncharacterized protein.	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.843
B0A49_02025	B0A49_05004	A0A4U0XEC9	A0A4U0XHM4	Uncharacterized protein.	Malate synthase, glyoxysomal.	0.803
B0A49_02025	B0A49_06264	A0A4U0XEC9	A0A4V5NFK0	Uncharacterized protein.	DAO domain-containing protein.	0.826
B0A49_02025	B0A49_09012	A0A4U0XEC9	A0A4U0WDJ6	Uncharacterized protein.	Glycerol-3-phosphate dehydrogenase [NAD(+)].	0.508
B0A49_02025	B0A49_10319	A0A4U0XEC9	A0A4U0X3A0	Uncharacterized protein.	Malate synthase; Belongs to the malate synthase family.	0.803
B0A49_02025	B0A49_11082	A0A4U0XEC9	A0A4U0WT03	Uncharacterized protein.	Uncharacterized protein.	0.800
B0A49_02025	B0A49_12508	A0A4U0XEC9	A0A4U0W673	Uncharacterized protein.	Fumarate hydratase, mitochondrial.	0.800
B0A49_02025	B0A49_13992	A0A4U0XEC9	A0A4U0UKQ3	Uncharacterized protein.	Fumarate hydratase, mitochondrial.	0.800
B0A49_02026	B0A49_02025	A0A4U0XE05	A0A4U0XEC9	Putative ATP-citrate synthase subunit 1.	Uncharacterized protein.	0.929
B0A49_02026	B0A49_03885	A0A4U0XE05	A0A4U0XBB5	Putative ATP-citrate synthase subunit 1.	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	0.844
B0A49_02026	B0A49_05004	A0A4U0XE05	A0A4U0XHM4	Putative ATP-citrate synthase subunit 1.	Malate synthase, glyoxysomal.	0.803
B0A49_02026	B0A49_06264	A0A4U0XE05	A0A4V5NFK0	Putative ATP-citrate synthase subunit 1.	DAO domain-containing protein.	0.826
B0A49_02026	B0A49_09012	A0A4U0XE05	A0A4U0WDJ6	Putative ATP-citrate synthase subunit 1.	Glycerol-3-phosphate dehydrogenase [NAD(+)].	0.508
B0A49_02026	B0A49_10319	A0A4U0XE05	A0A4U0X3A0	Putative ATP-citrate synthase subunit 1.	Malate synthase; Belongs to the malate synthase family.	0.803
B0A49_02026	B0A49_11082	A0A4U0XE05	A0A4U0WT03	Putative ATP-citrate synthase subunit 1.	Uncharacterized protein.	0.800
B0A49_02026	B0A49_12508	A0A4U0XE05	A0A4U0W673	Putative ATP-citrate synthase subunit 1.	Fumarate hydratase, mitochondrial.	0.800
B0A49_02026	B0A49_13992	A0A4U0XE05	A0A4U0UKQ3	Putative ATP-citrate synthase subunit 1.	Fumarate hydratase, mitochondrial.	0.800
B0A49_02681	B0A49_06264	A0A4U0XQE4	A0A4V5NFK0	Uncharacterized protein.	DAO domain-containing protein.	0.896
B0A49_03885	B0A49_02025	A0A4U0XBB5	A0A4U0XEC9	NAD-specific glutamate dehydrogenase; NAD(+)-dependent glutamate dehydrogenase which degrades glutamate to ammonia and alpha-ketoglutarate. Belongs to the Glu/Leu/Phe/Val dehydrogenases family.	Uncharacterized protein.	0.843

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Network Stats

number of nodes:

11

number of edges:

34

average node degree:

6.18

avg. local clustering coefficient:

0.927

expected number of edges:

13

PPI enrichment p-value:

9.31e-07

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006260

DNA replication

8 of 37

1.85

3.97

2.29e-11

GO:0034654

Nucleobase-containing compound biosynthetic process

11 of 159

1.35

2.42

1.33e-12

GO:0009059

Macromolecule biosynthetic process

10 of 244

1.12

1.52

4.64e-09

GO:0090304

Nucleic acid metabolic process

10 of 304

1.03

1.27

3.25e-08

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003887

DNA-directed DNA polymerase activity

8 of 12

2.34

6.43

1.10e-14

GO:0016779

Nucleotidyltransferase activity

10 of 52

1.8

4.51

8.81e-15

GO:0140640

Catalytic activity, acting on a nucleic acid

10 of 182

1.25

1.93

2.93e-10

GO:0004527

Exonuclease activity

4 of 23

1.75

1.9

5.82e-05

GO:0003677

DNA binding

9 of 262

1.05

1.25

3.07e-07

(more ...)

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0061695

Transferase complex, transferring phosphorus-containing groups

7 of 15

2.18

5.06

5.31e-12

GO:0009360

DNA polymerase III complex

5 of 5

2.51

4.68

6.75e-10

GO:0140535

Intracellular protein-containing complex

7 of 26

1.94

4.16

4.39e-11

GO:1902494

Catalytic complex

8 of 79

1.52

2.69

4.87e-10

GO:0000428

DNA-directed RNA polymerase complex

2 of 7

1.97

1.17

0.0055

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:634

DNA polymerase activity

8 of 10

2.41

6.66

8.72e-15

CL:637

DNA polymerase complex

5 of 5

2.51

4.37

3.19e-09

CL:279

RNA polymerase

2 of 5

2.11

0.9

0.0207

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

woc03030

DNA replication

8 of 17

2.18

5.85

2.91e-14

woc03430

Mismatch repair

8 of 18

2.16

5.78

2.91e-14

woc03440

Homologous recombination

8 of 22

2.07

5.42

5.22e-14

woc03020

RNA polymerase

2 of 4

2.21

1.31

0.0035

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009360

DNA polymerase III complex

8 of 9

2.46

7.05

1.78e-15

GOCC:0061695

Transferase complex, transferring phosphorus-containing groups

10 of 59

1.74

4.33

3.87e-15

GOCC:1902494

Catalytic complex

11 of 200

1.25

2.08

1.38e-12

GOCC:0044776

DNA polymerase III, core complex

2 of 2

2.51

1.48

0.0019

GOCC:0005622

Intracellular

11 of 1359

0.42

0.35

0.0011

Annotated Keywords (UniProt)

keyword

description

count in network

strength

signal

false discovery rate

KW-0239

DNA-directed DNA polymerase

4 of 7

2.27

2.92

1.71e-06

KW-0548

Nucleotidyltransferase

6 of 31

1.8

2.9

7.69e-08

KW-0235

DNA replication

4 of 19

1.83

2.07

3.00e-05

KW-0240

DNA-directed RNA polymerase

2 of 6

2.03

1.05

0.0103

KW-0808

Transferase

7 of 311

0.86

0.74

0.00053

Protein Domains (SMART)

domain

description

count in network

strength

signal

false discovery rate

SM00479

Exonuclease domain in DNA-polymerase alpha and epsilon chain, ribonuclease T and other exonucleases

2 of 4

2.21

0.99

0.0143

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