B0A49_01216 protein (Cryomyces minteri) - STRING interaction network

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

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Gene Fusion

Cooccurrence

Coexpression

Experiments

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[Homology]

Score

B0A49_01216

Uncharacterized protein. (545 aa)

Predicted Functional Partners:

B0A49_07634

0.996

B0A49_00650

0.993

B0A49_06608

0.986

B0A49_04324

0.986

B0A49_13583

0.826

B0A49_13762

0.826

B0A49_12315

0.826

B0A49_13154

0.826

B0A49_09721

0.826

B0A49_11514

0.826

Your Current Organism:

Cryomyces minteri

NCBI taxonomy Id: 331657
Other names: C. minteri, CBS 116302, CBS 116302 (ex-type); CCFEE 5187, CCFEE 5187

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
B0A49_00650	B0A49_01216	A0A4U0Y0C5	A0A4V5NHH9	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	Uncharacterized protein.	0.993
B0A49_00650	B0A49_11514	A0A4U0Y0C5	A0A4U0W0L5	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.	0.415
B0A49_01216	B0A49_00650	A0A4V5NHH9	A0A4U0Y0C5	Uncharacterized protein.	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.993
B0A49_01216	B0A49_04324	A0A4V5NHH9	A0A4U0X6M4	Uncharacterized protein.	Uncharacterized protein.	0.986
B0A49_01216	B0A49_06608	A0A4V5NHH9	A0A4U0WH53	Uncharacterized protein.	Uncharacterized protein.	0.986
B0A49_01216	B0A49_07634	A0A4V5NHH9	A0A4U0X4B6	Uncharacterized protein.	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.996
B0A49_01216	B0A49_09721	A0A4V5NHH9	A0A4U0VYB1	Uncharacterized protein.	Cupin_2 domain-containing protein.	0.826
B0A49_01216	B0A49_11514	A0A4V5NHH9	A0A4U0W0L5	Uncharacterized protein.	Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.	0.826
B0A49_01216	B0A49_12315	A0A4V5NHH9	A0A4U0V306	Uncharacterized protein.	Cupin_2 domain-containing protein.	0.826
B0A49_01216	B0A49_13154	A0A4V5NHH9	A0A4U0VD99	Uncharacterized protein.	NtCtMGAM_N domain-containing protein.	0.826
B0A49_01216	B0A49_13583	A0A4V5NHH9	A0A4U0UVN9	Uncharacterized protein.	NtCtMGAM_N domain-containing protein.	0.826
B0A49_01216	B0A49_13762	A0A4V5NHH9	A0A4U0UXA7	Uncharacterized protein.	NtCtMGAM_N domain-containing protein.	0.826
B0A49_04324	B0A49_01216	A0A4U0X6M4	A0A4V5NHH9	Uncharacterized protein.	Uncharacterized protein.	0.986
B0A49_06608	B0A49_01216	A0A4U0WH53	A0A4V5NHH9	Uncharacterized protein.	Uncharacterized protein.	0.986
B0A49_07634	B0A49_01216	A0A4U0X4B6	A0A4V5NHH9	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	Uncharacterized protein.	0.996
B0A49_07634	B0A49_11514	A0A4U0X4B6	A0A4U0W0L5	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.	0.439
B0A49_09721	B0A49_01216	A0A4U0VYB1	A0A4V5NHH9	Cupin_2 domain-containing protein.	Uncharacterized protein.	0.826
B0A49_11514	B0A49_00650	A0A4U0W0L5	A0A4U0Y0C5	Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.415
B0A49_11514	B0A49_01216	A0A4U0W0L5	A0A4V5NHH9	Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.	Uncharacterized protein.	0.826
B0A49_11514	B0A49_07634	A0A4U0W0L5	A0A4U0X4B6	Alpha-glucosidase; Belongs to the glycosyl hydrolase 31 family.	Gal_mutarotas_2 domain-containing protein; Belongs to the glycosyl hydrolase 31 family.	0.439

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Network Stats

number of nodes:

11

number of edges:

54

average node degree:

9.82

avg. local clustering coefficient:

0.982

expected number of edges:

11

PPI enrichment p-value:

< 1.0e-16

your network has significantly more interactions
than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0009231

Riboflavin biosynthetic process

4 of 8

2.65

3.26

8.05e-07

GO:0042364

Water-soluble vitamin biosynthetic process

5 of 31

2.16

2.99

8.05e-07

GO:0044283

Small molecule biosynthetic process

6 of 412

1.11

0.96

0.00088

GO:0018130

Heterocycle biosynthetic process

6 of 482

1.05

0.85

0.0018

GO:0044271

Cellular nitrogen compound biosynthetic process

7 of 770

0.91

0.73

0.0017

(more ...)

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:9972

Riboflavin metabolic process, and Response of Mtb to phagocytosis

6 of 11

2.69

5.77

7.85e-12

CL:9760

Mixed, incl. Metabolism of nucleotides, and Metabolism of water-soluble vitamins and cofactors

7 of 164

1.58

2.42

1.15e-07

CL:9976

Riboflavin metabolic process

2 of 5

2.55

1.14

0.0082

KEGG Pathways

pathway

description

count in network

strength

signal

false discovery rate

map00740

Riboflavin metabolism

5 of 28

2.2

3.7

2.14e-08

map01110

Biosynthesis of secondary metabolites

6 of 860

0.79

0.54

0.0109

map01100

Metabolic pathways

9 of 2837

0.45

0.32

0.0216

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-9637690

Response of Mtb to phagocytosis

2 of 4

2.65

0.99

0.0162

MAP-9637687

Suppression of phagosomal maturation

2 of 4

2.65

0.99

0.0162

MAP-9636383

Prevention of phagosomal-lysosomal fusion

2 of 4

2.65

0.99

0.0162

MAP-9635486

Infection with Mycobacterium tuberculosis

2 of 6

2.47

0.98

0.0162

Subcellular Localization (COMPARTMENTS)

compartment

description

count in network

strength

signal

false discovery rate

GOCC:0009349

Riboflavin synthase complex

2 of 4

2.65

0.98

0.0166

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