STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ruvCCrossover junction endodeoxyribonuclease RuvC; Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group. (186 aa)    
Predicted Functional Partners:
ruvA
Holliday junction DNA helicase RuvA; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB.
 
 
 0.923
ruvB
Holliday junction DNA helicase RuvB; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing.
 
 
 0.897
ACE03505.1
PFAM: protein of unknown function DUF28; KEGG: cch:Cag_0165 hypothetical protein.
 
  
 0.807
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
 
   
 0.777
ACE03507.1
PFAM: CDP-alcohol phosphatidyltransferase; KEGG: plt:Plut_1641 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.704
pheA
PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: cte:CT1666 prephenate dehydratase.
       0.509
recX
Regulatory protein RecX; Modulates RecA activity; Belongs to the RecX family.
  
  
 0.495
ACE04713.1
TIGRFAM: single-stranded-DNA-specific exonuclease RecJ; PFAM: phosphoesterase RecJ domain protein; phosphoesterase DHHA1; KEGG: pvi:Cvib_0510 single-stranded-DNA-specific exonuclease RecJ.
 
 
 
 0.447
recO
DNA repair protein RecO; Involved in DNA repair and RecF pathway recombination.
 
  
 0.429
ACE03006.1
PFAM: protein of unknown function UPF0102; KEGG: pvi:Cvib_0014 hypothetical protein; Belongs to the UPF0102 family.
 
     0.406
Your Current Organism:
Chlorobium phaeobacteroides BS1
NCBI taxonomy Id: 331678
Other names: C. phaeobacteroides BS1, Chlorobium phaeobacteroides MN1, Chlorobium phaeobacteroides str. BS1, Chlorobium phaeobacteroides strain BS1
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