| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACE03333.1 | birA | Cphamn1_0366 | Cphamn1_2459 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.438 |
| ACE03333.1 | coaD | Cphamn1_0366 | Cphamn1_1109 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.935 |
| ACE03333.1 | coaX | Cphamn1_0366 | Cphamn1_0958 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.925 |
| ACE03333.1 | panC | Cphamn1_0366 | Cphamn1_0553 | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.875 |
| ACE03901.1 | ACE03902.1 | Cphamn1_0956 | Cphamn1_0957 | PFAM: transposase IS4 family protein; KEGG: mes:Meso_4308 transposase, IS4. | KEGG: cte:CT1409 hypothetical protein. | 0.533 |
| ACE03901.1 | coaX | Cphamn1_0956 | Cphamn1_0958 | PFAM: transposase IS4 family protein; KEGG: mes:Meso_4308 transposase, IS4. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.479 |
| ACE03902.1 | ACE03901.1 | Cphamn1_0957 | Cphamn1_0956 | KEGG: cte:CT1409 hypothetical protein. | PFAM: transposase IS4 family protein; KEGG: mes:Meso_4308 transposase, IS4. | 0.533 |
| ACE03902.1 | coaX | Cphamn1_0957 | Cphamn1_0958 | KEGG: cte:CT1409 hypothetical protein. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.693 |
| ACE04723.1 | coaX | Cphamn1_1805 | Cphamn1_0958 | Penicillin-binding protein 2; KEGG: plt:Plut_0571 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.425 |
| birA | ACE03333.1 | Cphamn1_2459 | Cphamn1_0366 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.438 |
| birA | coaX | Cphamn1_2459 | Cphamn1_0958 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.725 |
| birA | panC | Cphamn1_2459 | Cphamn1_0553 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Pantoate/beta-alanine ligase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. | 0.516 |
| birA | panD | Cphamn1_2459 | Cphamn1_0412 | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | Aspartate 1-decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. | 0.484 |
| coaD | ACE03333.1 | Cphamn1_1109 | Cphamn1_0366 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.935 |
| coaD | coaX | Cphamn1_1109 | Cphamn1_0958 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | 0.952 |
| coaX | ACE03333.1 | Cphamn1_0958 | Cphamn1_0366 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Phosphopantothenoylcysteine decarboxylase/phosphopantothenate/cysteine ligase; Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4- phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine; In the C-terminal section; belongs to the PPC synthetase family. | 0.925 |
| coaX | ACE03901.1 | Cphamn1_0958 | Cphamn1_0956 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | PFAM: transposase IS4 family protein; KEGG: mes:Meso_4308 transposase, IS4. | 0.479 |
| coaX | ACE03902.1 | Cphamn1_0958 | Cphamn1_0957 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | KEGG: cte:CT1409 hypothetical protein. | 0.693 |
| coaX | ACE04723.1 | Cphamn1_0958 | Cphamn1_1805 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | Penicillin-binding protein 2; KEGG: plt:Plut_0571 peptidoglycan glycosyltransferase; TIGRFAM: penicillin-binding protein 2; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain. | 0.425 |
| coaX | birA | Cphamn1_0958 | Cphamn1_2459 | Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.725 |