Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ACE04110.1PFAM: AMP-dependent synthetase and ligase; KEGG: cch:Cag_1125 propionate--CoA ligase. (631 aa)    
Predicted Functional Partners:
ACE04436.1
TIGRFAM: quinone oxidoreductase, YhdH/YhfP family; PFAM: Alcohol dehydrogenase zinc-binding domain protein; Alcohol dehydrogenase GroES domain protein; KEGG: pca:Pcar_1356 putative NADPH:quinone reductase/Zn-dependent oxidoreductase.
   
 
 0.912
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 
0.911
ACE05030.1
PFAM: Aldehyde Dehydrogenase_; KEGG: cte:CT1886 aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.
 
 0.855
ACE04107.1
methylmalonyl-CoA mutase, large subunit; KEGG: cch:Cag_1223 methylmalonyl-CoA mutase; TIGRFAM: methylmalonyl-CoA mutase, large subunit; PFAM: methylmalonyl-CoA mutase; cobalamin B12-binding domain protein.
     
 0.814
ACE04109.1
TIGRFAM: methylmalonyl-CoA epimerase; PFAM: Glyoxalase/bleomycin resistance protein/dioxygenase; KEGG: cch:Cag_1126 hypothetical protein.
  
  
 0.810
ACE04108.1
KEGG: cch:Cag_1127 acetyl-CoA carboxylase alpha subunit-like.
       0.750
ACE03974.1
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: plt:Plut_1072 2-oxoacid:ferredoxin oxidoreductase, alpha subunit.
  
 
 0.681
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
    
 0.629
gyrB
DNA gyrase, B subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner.
     
 0.614
ACE04106.1
TIGRFAM: LAO/AO transport system ATPase; PFAM: ArgK protein; KEGG: cch:Cag_1237 arginine/ornithine transport system ATPase.
       0.605
Your Current Organism:
Chlorobium phaeobacteroides BS1
NCBI taxonomy Id: 331678
Other names: C. phaeobacteroides BS1, Chlorobium phaeobacteroides MN1, Chlorobium phaeobacteroides str. BS1, Chlorobium phaeobacteroides strain BS1
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