| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACE03264.1 | ACE03268.1 | Cphamn1_0295 | Cphamn1_0299 | KEGG: cte:CT2035 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | KEGG: plt:Plut_1983 aspartate kinase region; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | 0.990 |
| ACE03264.1 | ACE03759.1 | Cphamn1_0295 | Cphamn1_0808 | KEGG: cte:CT2035 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 4-hydroxythreonine-4-phosphate dehydrogenase; KEGG: cte:CT0591 pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; Belongs to the PdxA family. | 0.903 |
| ACE03264.1 | ACE04492.1 | Cphamn1_0295 | Cphamn1_1569 | KEGG: cte:CT2035 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rma:Rmag_0627 D-3-phosphoglycerate dehydrogenase. | 0.587 |
| ACE03264.1 | serC | Cphamn1_0295 | Cphamn1_1568 | KEGG: cte:CT2035 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.935 |
| ACE03268.1 | ACE03264.1 | Cphamn1_0299 | Cphamn1_0295 | KEGG: plt:Plut_1983 aspartate kinase region; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | KEGG: cte:CT2035 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.990 |
| ACE03268.1 | ACE03309.1 | Cphamn1_0299 | Cphamn1_0341 | KEGG: plt:Plut_1983 aspartate kinase region; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | KEGG: cte:CT0173 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3. | 0.577 |
| ACE03268.1 | ACE04492.1 | Cphamn1_0299 | Cphamn1_1569 | KEGG: plt:Plut_1983 aspartate kinase region; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rma:Rmag_0627 D-3-phosphoglycerate dehydrogenase. | 0.768 |
| ACE03268.1 | aroA | Cphamn1_0299 | Cphamn1_2175 | KEGG: plt:Plut_1983 aspartate kinase region; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | 3-phosphoshikimate 1-carboxyvinyltransferase; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. | 0.584 |
| ACE03268.1 | glyA | Cphamn1_0299 | Cphamn1_0630 | KEGG: plt:Plut_1983 aspartate kinase region; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.522 |
| ACE03268.1 | pheA | Cphamn1_0299 | Cphamn1_0541 | KEGG: plt:Plut_1983 aspartate kinase region; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | PFAM: prephenate dehydratase; amino acid-binding ACT domain protein; KEGG: cte:CT1666 prephenate dehydratase. | 0.598 |
| ACE03268.1 | serC | Cphamn1_0299 | Cphamn1_1568 | KEGG: plt:Plut_1983 aspartate kinase region; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.610 |
| ACE03309.1 | ACE03268.1 | Cphamn1_0341 | Cphamn1_0299 | KEGG: cte:CT0173 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3. | KEGG: plt:Plut_1983 aspartate kinase region; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding. | 0.577 |
| ACE03309.1 | ACE04492.1 | Cphamn1_0341 | Cphamn1_1569 | KEGG: cte:CT0173 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3. | PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rma:Rmag_0627 D-3-phosphoglycerate dehydrogenase. | 0.445 |
| ACE03309.1 | glyA | Cphamn1_0341 | Cphamn1_0630 | KEGG: cte:CT0173 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.943 |
| ACE03309.1 | serC | Cphamn1_0341 | Cphamn1_1568 | KEGG: cte:CT0173 phosphoserine phosphatase; TIGRFAM: phosphoserine phosphatase SerB; HAD-superfamily hydrolase, subfamily IB (PSPase-like); PFAM: amino acid-binding ACT domain protein; Haloacid dehalogenase domain protein hydrolase; Haloacid dehalogenase domain protein hydrolase type 3. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.952 |
| ACE03600.1 | ACE05138.1 | Cphamn1_0642 | Cphamn1_2233 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mta:Moth_1706 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: plt:Plut_0234 cysteine synthase K/M/A. | 0.904 |
| ACE03600.1 | serC | Cphamn1_0642 | Cphamn1_1568 | TIGRFAM: cysteine synthase; cysteine synthase A; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit; KEGG: mta:Moth_1706 cysteine synthase; Belongs to the cysteine synthase/cystathionine beta- synthase family. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.912 |
| ACE03759.1 | ACE03264.1 | Cphamn1_0808 | Cphamn1_0295 | 4-hydroxythreonine-4-phosphate dehydrogenase; KEGG: cte:CT0591 pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; Belongs to the PdxA family. | KEGG: cte:CT2035 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.903 |
| ACE03759.1 | serC | Cphamn1_0808 | Cphamn1_1568 | 4-hydroxythreonine-4-phosphate dehydrogenase; KEGG: cte:CT0591 pyridoxal phosphate biosynthetic protein PdxA; TIGRFAM: 4-hydroxythreonine-4-phosphate dehydrogenase; PFAM: Pyridoxal phosphate biosynthetic protein PdxA; Belongs to the PdxA family. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.913 |
| ACE04492.1 | ACE03264.1 | Cphamn1_1569 | Cphamn1_0295 | PFAM: amino acid-binding ACT domain protein; D-isomer specific 2-hydroxyacid dehydrogenase catalytic region; D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding; KEGG: rma:Rmag_0627 D-3-phosphoglycerate dehydrogenase. | KEGG: cte:CT2035 threonine synthase; TIGRFAM: threonine synthase; PFAM: Pyridoxal-5'-phosphate-dependent protein beta subunit. | 0.587 |