STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACE04665.1PFAM: pyruvate carboxyltransferase; KEGG: cch:Cag_1229 homocitrate synthase; Belongs to the alpha-IPM synthase/homocitrate synthase family. (383 aa)    
Predicted Functional Partners:
ACE03548.1
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cch:Cag_1730 pyruvate:ferredoxin (flavodoxin) oxidoreductase.
  
 
 0.945
leuA-2
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
  
 
0.922
ACE04642.1
KEGG: cte:CT0612 2-isopropylmalate synthase; TIGRFAM: 2-isopropylmalate synthase/homocitrate synthase family protein; PFAM: pyruvate carboxyltransferase; LeuA allosteric (dimerisation) domain; Belongs to the alpha-IPM synthase/homocitrate synthase family.
  
  
 
0.921
ACE03296.1
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cte:CT0163 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit.
  
 
 0.916
ACE03974.1
PFAM: pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: plt:Plut_1072 2-oxoacid:ferredoxin oxidoreductase, alpha subunit.
  
 
 0.916
acsA
acetate/CoA ligase; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 
 0.914
ACE03295.1
PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: cch:Cag_0365 2-oxoglutarate ferredoxin oxidoreductase subunit beta.
   
 
 0.904
ACE03975.1
TIGRFAM: pyruvate ferredoxin/flavodoxin oxidoreductase, beta subunit; PFAM: thiamine pyrophosphate protein domain protein TPP-binding; KEGG: plt:Plut_1073 2-oxoacid:acceptor oxidoreductase, beta subunit, pyruvate/2-ketoisovalerate.
   
 
 0.904
ACE03290.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
  
 
  0.903
leuA
2-isopropylmalate synthase; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 2 subfamily.
     
 
0.900
Your Current Organism:
Chlorobium phaeobacteroides BS1
NCBI taxonomy Id: 331678
Other names: C. phaeobacteroides BS1, Chlorobium phaeobacteroides MN1, Chlorobium phaeobacteroides str. BS1, Chlorobium phaeobacteroides strain BS1
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