| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACE04341.1 | ACE04740.1 | Cphamn1_1413 | Cphamn1_1822 | TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: aoe:Clos_1897 DNA-cytosine methyltransferase. | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | 0.900 |
| ACE04341.1 | metK | Cphamn1_1413 | Cphamn1_1640 | TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: aoe:Clos_1897 DNA-cytosine methyltransferase. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.920 |
| ACE04739.1 | ACE04740.1 | Cphamn1_1821 | Cphamn1_1822 | PFAM: glycosyl transferase group 1; KEGG: plt:Plut_0552 glycosyl transferase. | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | 0.485 |
| ACE04740.1 | ACE04341.1 | Cphamn1_1822 | Cphamn1_1413 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | TIGRFAM: DNA-cytosine methyltransferase; PFAM: C-5 cytosine-specific DNA methylase; KEGG: aoe:Clos_1897 DNA-cytosine methyltransferase. | 0.900 |
| ACE04740.1 | ACE04739.1 | Cphamn1_1822 | Cphamn1_1821 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | PFAM: glycosyl transferase group 1; KEGG: plt:Plut_0552 glycosyl transferase. | 0.485 |
| ACE04740.1 | ACE04741.1 | Cphamn1_1822 | Cphamn1_1823 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | PFAM: major facilitator superfamily MFS_1; KEGG: rba:RB11273 bicyclomycin resistance protein. | 0.471 |
| ACE04740.1 | ACE04956.1 | Cphamn1_1822 | Cphamn1_2046 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | KEGG: pvi:Cvib_0418 transcriptional regulator, fis family. | 0.522 |
| ACE04740.1 | ACE05002.1 | Cphamn1_1822 | Cphamn1_2093 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | 0.900 |
| ACE04740.1 | cysS | Cphamn1_1822 | Cphamn1_2264 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | KEGG: plt:Plut_0211 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.415 |
| ACE04740.1 | lolD | Cphamn1_1822 | Cphamn1_0461 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | ABC transporter-related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.412 |
| ACE04740.1 | lolD-2 | Cphamn1_1822 | Cphamn1_0860 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | ABC transporter-related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.403 |
| ACE04740.1 | metK | Cphamn1_1822 | Cphamn1_1640 | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.900 |
| ACE04741.1 | ACE04740.1 | Cphamn1_1823 | Cphamn1_1822 | PFAM: major facilitator superfamily MFS_1; KEGG: rba:RB11273 bicyclomycin resistance protein. | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | 0.471 |
| ACE04956.1 | ACE04740.1 | Cphamn1_2046 | Cphamn1_1822 | KEGG: pvi:Cvib_0418 transcriptional regulator, fis family. | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | 0.522 |
| ACE05002.1 | ACE04740.1 | Cphamn1_2093 | Cphamn1_1822 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | 0.900 |
| ACE05002.1 | metK | Cphamn1_2093 | Cphamn1_1640 | Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.947 |
| cysS | ACE04740.1 | Cphamn1_2264 | Cphamn1_1822 | KEGG: plt:Plut_0211 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | 0.415 |
| cysS | lolD | Cphamn1_2264 | Cphamn1_0461 | KEGG: plt:Plut_0211 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. | ABC transporter-related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | 0.405 |
| lolD | ACE04740.1 | Cphamn1_0461 | Cphamn1_1822 | ABC transporter-related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | PFAM: S-adenosylmethionine synthetase (MAT); KEGG: cte:CT0540 S-adenosylmethionine synthase, archaeal-type. | 0.412 |
| lolD | cysS | Cphamn1_0461 | Cphamn1_2264 | ABC transporter-related protein; Part of the ABC transporter complex LolCDE involved in the translocation of mature outer membrane-directed lipoproteins, from the inner membrane to the periplasmic chaperone, LolA. Responsible for the formation of the LolA-lipoprotein complex in an ATP-dependent manner. | KEGG: plt:Plut_0211 cysteinyl-tRNA synthetase; TIGRFAM: cysteinyl-tRNA synthetase; PFAM: Cysteinyl-tRNA synthetase class Ia DALR; tRNA synthetase class I (M); Cysteinyl-tRNA synthetase class Ia; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.405 |