| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACE03388.1 | ACE03453.1 | Cphamn1_0423 | Cphamn1_0490 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pvi:Cvib_1538 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: pvi:Cvib_1468 para-aminobenzoate synthase, subunit I. | 0.464 |
| ACE03388.1 | ACE03462.1 | Cphamn1_0423 | Cphamn1_0499 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pvi:Cvib_1538 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.996 |
| ACE03388.1 | ACE04543.1 | Cphamn1_0423 | Cphamn1_1623 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pvi:Cvib_1538 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.474 |
| ACE03388.1 | ACE05096.1 | Cphamn1_0423 | Cphamn1_2191 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pvi:Cvib_1538 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.434 |
| ACE03388.1 | ACE05097.1 | Cphamn1_0423 | Cphamn1_2192 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pvi:Cvib_1538 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | KEGG: cch:Cag_0230 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | 0.602 |
| ACE03388.1 | folE | Cphamn1_0423 | Cphamn1_1588 | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pvi:Cvib_1538 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | PFAM: GTP cyclohydrolase I; KEGG: cte:CT0781 GTP cyclohydrolase I. | 0.533 |
| ACE03453.1 | ACE03388.1 | Cphamn1_0490 | Cphamn1_0423 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: pvi:Cvib_1468 para-aminobenzoate synthase, subunit I. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pvi:Cvib_1538 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | 0.464 |
| ACE03453.1 | ACE03462.1 | Cphamn1_0490 | Cphamn1_0499 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: pvi:Cvib_1468 para-aminobenzoate synthase, subunit I. | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | 0.971 |
| ACE03453.1 | ACE04543.1 | Cphamn1_0490 | Cphamn1_1623 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: pvi:Cvib_1468 para-aminobenzoate synthase, subunit I. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.541 |
| ACE03453.1 | ACE05096.1 | Cphamn1_0490 | Cphamn1_2191 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: pvi:Cvib_1468 para-aminobenzoate synthase, subunit I. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.511 |
| ACE03453.1 | ACE05097.1 | Cphamn1_0490 | Cphamn1_2192 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: pvi:Cvib_1468 para-aminobenzoate synthase, subunit I. | KEGG: cch:Cag_0230 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | 0.708 |
| ACE03453.1 | birA | Cphamn1_0490 | Cphamn1_2459 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: pvi:Cvib_1468 para-aminobenzoate synthase, subunit I. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.560 |
| ACE03453.1 | folE | Cphamn1_0490 | Cphamn1_1588 | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: pvi:Cvib_1468 para-aminobenzoate synthase, subunit I. | PFAM: GTP cyclohydrolase I; KEGG: cte:CT0781 GTP cyclohydrolase I. | 0.512 |
| ACE03462.1 | ACE03388.1 | Cphamn1_0499 | Cphamn1_0423 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pvi:Cvib_1538 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family. | 0.996 |
| ACE03462.1 | ACE03453.1 | Cphamn1_0499 | Cphamn1_0490 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: pvi:Cvib_1468 para-aminobenzoate synthase, subunit I. | 0.971 |
| ACE03462.1 | ACE04543.1 | Cphamn1_0499 | Cphamn1_1623 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.481 |
| ACE03462.1 | ACE05096.1 | Cphamn1_0499 | Cphamn1_2191 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | 0.984 |
| ACE03462.1 | ACE05097.1 | Cphamn1_0499 | Cphamn1_2192 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | KEGG: cch:Cag_0230 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. | 0.999 |
| ACE03462.1 | birA | Cphamn1_0499 | Cphamn1_2459 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.480 |
| ACE03462.1 | folE | Cphamn1_0499 | Cphamn1_1588 | Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives. | PFAM: GTP cyclohydrolase I; KEGG: cte:CT0781 GTP cyclohydrolase I. | 0.962 |