STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACE05097.1KEGG: cch:Cag_0230 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase, HppK; TIGRFAM: 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase; PFAM: 78-dihydro-6-hydroxymethylpterin-pyrophosphokinase HPPK. (174 aa)    
Predicted Functional Partners:
ACE03462.1
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 0.999
ACE05096.1
Dihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin.
 
 
 0.997
folE
PFAM: GTP cyclohydrolase I; KEGG: cte:CT0781 GTP cyclohydrolase I.
  
 0.994
ACE04018.1
PFAM: beta-lactamase domain protein; KEGG: cte:CT0187 hypothetical protein.
     
  0.900
ACE03585.1
KEGG: sru:SRU_1567 hypothetical protein.
  
  
 0.717
ACE03453.1
TIGRFAM: para-aminobenzoate synthase, subunit I; PFAM: Chorismate binding-like; KEGG: pvi:Cvib_1468 para-aminobenzoate synthase, subunit I.
 
  
 0.708
ACE03388.1
TIGRFAM: FolC bifunctional protein; PFAM: cytoplasmic peptidoglycan synthetase domain protein; Mur ligase middle domain protein; KEGG: pvi:Cvib_1538 FolC bifunctional protein; Belongs to the folylpolyglutamate synthase family.
 
  
 0.602
ACE05095.1
KEGG: plt:Plut_0270 nicotinate-nucleotide pyrophosphorylase; TIGRFAM: nicotinate-nucleotide pyrophosphorylase; PFAM: Quinolinate phosphoribosyl transferase; Belongs to the NadC/ModD family.
     
 0.580
ACE04543.1
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.575
ACE04785.1
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.514
Your Current Organism:
Chlorobium phaeobacteroides BS1
NCBI taxonomy Id: 331678
Other names: C. phaeobacteroides BS1, Chlorobium phaeobacteroides MN1, Chlorobium phaeobacteroides str. BS1, Chlorobium phaeobacteroides strain BS1
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