| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| ACE03475.1 | nadK | Cphamn1_0512 | Cphamn1_2432 | PFAM: Alkaline phosphatase; KEGG: pvi:Cvib_1725 alkaline phosphatase; Belongs to the alkaline phosphatase family. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.507 |
| ACE03490.1 | nadD | Cphamn1_0527 | Cphamn1_2488 | PFAM: Silent information regulator protein Sir2; KEGG: pis:Pisl_0793 NAD-dependent deacetylase. | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.916 |
| ACE03490.1 | nadE | Cphamn1_0527 | Cphamn1_1813 | PFAM: Silent information regulator protein Sir2; KEGG: pis:Pisl_0793 NAD-dependent deacetylase. | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.913 |
| ACE03490.1 | nadK | Cphamn1_0527 | Cphamn1_2432 | PFAM: Silent information regulator protein Sir2; KEGG: pis:Pisl_0793 NAD-dependent deacetylase. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.912 |
| ACE03521.1 | nadK | Cphamn1_0560 | Cphamn1_2432 | KEGG: plt:Plut_1631 protease IV; TIGRFAM: signal peptide peptidase SppA, 67K type; signal peptide peptidase SppA, 36K type; PFAM: peptidase S49. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.547 |
| ACE05324.1 | ACE05326.1 | Cphamn1_2429 | Cphamn1_2431 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | PFAM: Prephenate dehydrogenase; KEGG: pvi:Cvib_1692 prephenate dehydrogenase. | 0.542 |
| ACE05324.1 | ACE05328.1 | Cphamn1_2429 | Cphamn1_2433 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | KEGG: cte:CT0086 hypothetical protein. | 0.454 |
| ACE05324.1 | nadK | Cphamn1_2429 | Cphamn1_2432 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.545 |
| ACE05324.1 | pyrE | Cphamn1_2429 | Cphamn1_2430 | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.551 |
| ACE05326.1 | ACE05324.1 | Cphamn1_2431 | Cphamn1_2429 | PFAM: Prephenate dehydrogenase; KEGG: pvi:Cvib_1692 prephenate dehydrogenase. | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.542 |
| ACE05326.1 | ACE05328.1 | Cphamn1_2431 | Cphamn1_2433 | PFAM: Prephenate dehydrogenase; KEGG: pvi:Cvib_1692 prephenate dehydrogenase. | KEGG: cte:CT0086 hypothetical protein. | 0.728 |
| ACE05326.1 | nadK | Cphamn1_2431 | Cphamn1_2432 | PFAM: Prephenate dehydrogenase; KEGG: pvi:Cvib_1692 prephenate dehydrogenase. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.796 |
| ACE05326.1 | pyrE | Cphamn1_2431 | Cphamn1_2430 | PFAM: Prephenate dehydrogenase; KEGG: pvi:Cvib_1692 prephenate dehydrogenase. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.773 |
| ACE05328.1 | ACE05324.1 | Cphamn1_2433 | Cphamn1_2429 | KEGG: cte:CT0086 hypothetical protein. | Holliday junction resolvase YqgF; Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA; Belongs to the YqgF nuclease family. | 0.454 |
| ACE05328.1 | ACE05326.1 | Cphamn1_2433 | Cphamn1_2431 | KEGG: cte:CT0086 hypothetical protein. | PFAM: Prephenate dehydrogenase; KEGG: pvi:Cvib_1692 prephenate dehydrogenase. | 0.728 |
| ACE05328.1 | nadK | Cphamn1_2433 | Cphamn1_2432 | KEGG: cte:CT0086 hypothetical protein. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.704 |
| ACE05328.1 | pyrE | Cphamn1_2433 | Cphamn1_2430 | KEGG: cte:CT0086 hypothetical protein. | Orotate phosphoribosyltransferase; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). | 0.754 |
| dxs | nadK | Cphamn1_1826 | Cphamn1_2432 | Deoxyxylulose-5-phosphate synthase; Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D- xylulose-5-phosphate (DXP); Belongs to the transketolase family. DXPS subfamily. | ATP-NAD/AcoX kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.650 |
| nadD | ACE03490.1 | Cphamn1_2488 | Cphamn1_0527 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | PFAM: Silent information regulator protein Sir2; KEGG: pis:Pisl_0793 NAD-dependent deacetylase. | 0.916 |
| nadD | nadE | Cphamn1_2488 | Cphamn1_1813 | Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | NAD+ synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.942 |