Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
birAbiotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. (329 aa)    
Predicted Functional Partners:
bioB
Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family.
  
 
 0.985
ACE03181.1
PFAM: Radical SAM domain protein; KEGG: dol:Dole_3188 radical SAM domain protein.
  
 
 0.944
ACE03290.1
acetyl-CoA carboxylase, biotin carboxylase; This protein is a component of the acetyl coenzyme A carboxylase complex; first, biotin carboxylase catalyzes the carboxylation of the carrier protein and then the transcarboxylase transfers the carboxyl group to form malonyl-CoA.
 0.937
tadA
CMP/dCMP deaminase zinc-binding; Catalyzes the deamination of adenosine to inosine at the wobble position 34 of tRNA(Arg2); Belongs to the cytidine and deoxycytidylate deaminase family.
 
    0.930
ACE03103.1
PFAM: peptidase M22 glycoprotease; KEGG: plt:Plut_0096 protease, putative.
 
    0.925
ACE05351.1
8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: cte:CT0051 8-amino-7-oxononanoate synthase.
  
  
 0.844
ACE03136.1
Exodeoxyribonuclease III Xth; KEGG: cte:CT2136 AP (apurinic or apyrimidinic) endonuclease, Xth family; TIGRFAM: exodeoxyribonuclease III; exodeoxyribonuclease III Xth; PFAM: Endonuclease/exonuclease/phosphatase.
  
    0.760
coaX
Putative transcriptional acitvator, Baf family; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.
  
    0.734
ACE04451.1
PFAM: Polynucleotide adenylyltransferase region; metal-dependent phosphohydrolase HD sub domain; KEGG: cte:CT0990 polyA polymerase family protein; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
  
  
 0.727
ACE03152.1
3-oxoacyl-(acyl-carrier-protein) synthase 2; Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP.
 
   
 0.694
Your Current Organism:
Chlorobium phaeobacteroides BS1
NCBI taxonomy Id: 331678
Other names: C. phaeobacteroides BS1, Chlorobium phaeobacteroides MN1, Chlorobium phaeobacteroides str. BS1, Chlorobium phaeobacteroides strain BS1
Server load: low (10%) [HD]