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LIS1 protein (Eremothecium gossypii) - STRING interaction network
"LIS1" - Nuclear distribution protein PAC1 in Eremothecium gossypii
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query proteins and first shell of interactors
white nodes:
second shell of interactors
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proteins of unknown 3D structure
filled nodes:
some 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LIS1Nuclear distribution protein PAC1; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. Plays a central role in positioning the mitotic spindle at the bud neck during cell division. Targets cytoplasmic dynein to microtubule plus ends, thereby promoting dynein-mediated microtubule sliding along the bud cortex and consequently the movement of the mitotic spindle to the bud neck (461 aa)    
Predicted Functional Partners:
DYN1
Dynein heavy chain, cytoplasmic; Cytoplasmic dynein acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Required to maintain uniform nuclear distribution in hyphae. May play an important role in the proper orientation of the mitotic spindle into the budding daughter cell yeast. Probably required for normal progression of the cell cycle; Belongs to the dynein heavy chain family (4083 aa)
     
 
  0.968
AAS54074
AFR702Wp (497 aa)
       
 
  0.933
AAS50257
AAL109Wp (914 aa)
       
 
  0.925
AAS54834
AGR344Wp; Belongs to the CDP-alcohol phosphatidyltransferase class-I family (390 aa)
     
 
    0.900
AAS52151
Patatin-like phospholipase domain-containing protein; Lipid hydrolase (816 aa)
         
    0.900
AAS54532
AGR043Wp (3645 aa)
       
 
  0.893
AAS53798
Proteasome assembly chaperone 2; Involved in 20S proteasome assembly (296 aa)
           
  0.860
AAS51083
ACL145Wp (255 aa)
           
  0.860
KIP2
Kinesin-like protein KIP2; Required for assembly of the mitotic spindle (685 aa)
     
 
  0.846
AAS50912
ABR141Wp (363 aa)
       
 
  0.812
Your Current Organism:
Eremothecium gossypii
NCBI taxonomy Id: 33169
Other names: Ashbya gossypii, E. gossypii, Eremothecium gossypii, Eremothecium gossypii (Ashby & Nowell) Kurtzman, Nematospora gossypii
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