STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
EDP61360.1COG2099 Precorrin-6x reductase. (251 aa)    
Predicted Functional Partners:
cbiD-2
Cobalamin biosynthesis protein CbiD; Catalyzes the methylation of C-1 in cobalt-precorrin-5B to form cobalt-precorrin-6A.
 
 0.997
EDP61354.1
Precorrin-3B methylase; COG2073 Cobalamin biosynthesis protein CbiG.
 
  
 0.995
EDP61352.1
Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase; COG2241 Precorrin-6B methylase 1.
 
 
 0.988
EDP61351.1
precorrin-8X methylmutase; COG2082 Precorrin isomerase.
 
 
 0.985
EDP61353.1
COG2243 Precorrin-2 methylase; Belongs to the precorrin methyltransferase family.
 
 
 0.982
EDP61355.1
COG2875 Precorrin-4 methylase.
 
 
 0.981
cobQ
Cobyric acid synthase; Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
 
  
 0.941
cbiA
Cobyrinic acid a,c-diamide synthase CbiA; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.919
EDP62904.1
uroporphyrin-III C-methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. Belongs to the precorrin methyltransferase family. In the N-terminal section; belongs to the precorrin-2 dehydrogenase / sirohydrochlorin ferrochelatase family.
  
 
 0.880
EDP66053.1
COG1429 Cobalamin biosynthesis protein CobN and related Mg-chelatases.
 
   
 0.805
Your Current Organism:
alpha proteobacterium BAL199
NCBI taxonomy Id: 331869
Other names: a. proteobacterium BAL199
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