node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
FEN1 | PCL_05912 | A0A179HS02 | A0A179GBU0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase subunit Cdc27. | 0.690 |
FEN1 | VFPBJ_07313 | A0A179HS02 | A0A179HUD8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.876 |
FEN1 | VFPBJ_07388 | A0A179HS02 | A0A179GMY8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.910 |
FEN1 | VFPBJ_07980 | A0A179HS02 | A0A179H7B0 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase subunit delta-2. | 0.958 |
FEN1 | VFPFJ_02834 | A0A179HS02 | A0A179HUV2 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. | 0.837 |
FEN1 | VFPFJ_08018 | A0A179HS02 | A0A179H889 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.825 |
FEN1 | VFPFJ_09469 | A0A179HS02 | A0A179GSY8 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase epsilon subunit B. | 0.888 |
FEN1 | VFPFJ_09703 | A0A179HS02 | A0A179GUT1 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA helicase; Belongs to the MCM family. | 0.915 |
FEN1 | VFPFJ_11442 | A0A179HS02 | A0A179F7Y6 | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | DNA polymerase. | 0.951 |
PCL_05912 | FEN1 | A0A179GBU0 | A0A179HS02 | DNA polymerase subunit Cdc27. | Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] | 0.690 |
PCL_05912 | PCL_09417 | A0A179GBU0 | A0A179GSX4 | DNA polymerase subunit Cdc27. | DNA polymerase delta subunit 4. | 0.972 |
PCL_05912 | VFPBJ_07313 | A0A179GBU0 | A0A179HUD8 | DNA polymerase subunit Cdc27. | DNA primase; Belongs to the eukaryotic-type primase small subunit family. | 0.411 |
PCL_05912 | VFPBJ_07388 | A0A179GBU0 | A0A179GMY8 | DNA polymerase subunit Cdc27. | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. | 0.784 |
PCL_05912 | VFPBJ_07980 | A0A179GBU0 | A0A179H7B0 | DNA polymerase subunit Cdc27. | DNA polymerase subunit delta-2. | 0.998 |
PCL_05912 | VFPFJ_02834 | A0A179GBU0 | A0A179HUV2 | DNA polymerase subunit Cdc27. | DNA primase large subunit; DNA primase is the polymerase that synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication; Belongs to the eukaryotic-type primase large subunit family. | 0.620 |
PCL_05912 | VFPFJ_08018 | A0A179GBU0 | A0A179H889 | DNA polymerase subunit Cdc27. | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. | 0.457 |
PCL_05912 | VFPFJ_09469 | A0A179GBU0 | A0A179GSY8 | DNA polymerase subunit Cdc27. | DNA polymerase epsilon subunit B. | 0.666 |
PCL_05912 | VFPFJ_11442 | A0A179GBU0 | A0A179F7Y6 | DNA polymerase subunit Cdc27. | DNA polymerase. | 0.989 |
PCL_09417 | PCL_05912 | A0A179GSX4 | A0A179GBU0 | DNA polymerase delta subunit 4. | DNA polymerase subunit Cdc27. | 0.972 |
PCL_09417 | VFPBJ_07980 | A0A179GSX4 | A0A179H7B0 | DNA polymerase delta subunit 4. | DNA polymerase subunit delta-2. | 0.975 |