VFPBJ_08425 protein (Purpureocillium lilacinum)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:

Neighborhood

Gene Fusion

Cooccurrence

Coexpression

Experiments

Databases

Textmining

[Homology]

Score

VFPBJ_08425

Acetamidase. (559 aa)

Predicted Functional Partners:

VFPBJ_07355

0.665

VFPBJ_08426

0.532

VFPFJ_10152

0.508

Your Current Organism:

Purpureocillium lilacinum

NCBI taxonomy Id: 33203
Other names: ATCC 10114, CBS 284.36, CCRC 31616, CCRC:31616, DSM 846, IMI 027830, JCM 9332, NCTC 584, NRRL 895, P. lilacinum, Paecilomyces lilacinum, Paecilomyces lilacinus, Penicillium lilacinum, Purpureocillium lilacinum (Thom) Luangsa-ard, Houbraken, Hywel-Jones & Samson 2011, QM 7592, VKM F-3193

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
VFPBJ_07355	VFPBJ_08425	A0A179GMW8	A0A179GE09	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	Acetamidase.	0.665
VFPBJ_07355	VFPFJ_10152	A0A179GMW8	A0A179GL41	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	Aspartyl-tRNA synthetase.	0.988
VFPBJ_08425	VFPBJ_07355	A0A179GE09	A0A179GMW8	Acetamidase.	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	0.665
VFPBJ_08425	VFPBJ_08426	A0A179GE09	A0A179GYZ8	Acetamidase.	WLM domain-containing protein.	0.532
VFPBJ_08425	VFPFJ_10152	A0A179GE09	A0A179GL41	Acetamidase.	Aspartyl-tRNA synthetase.	0.508
VFPBJ_08426	VFPBJ_08425	A0A179GYZ8	A0A179GE09	WLM domain-containing protein.	Acetamidase.	0.532
VFPFJ_10152	VFPBJ_07355	A0A179GL41	A0A179GMW8	Aspartyl-tRNA synthetase.	Glutamyl-tRNA(Gln) amidotransferase subunit B, mitochondrial; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in the mitochondria. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln). Belongs to the GatB/GatE family. GatB subfamily.	0.988
VFPFJ_10152	VFPBJ_08425	A0A179GL41	A0A179GE09	Aspartyl-tRNA synthetase.	Acetamidase.	0.508

Network Stats

number of nodes:

11

number of edges:

26

average node degree:

4.73

avg. local clustering coefficient:

0.878

expected number of edges:

25

PPI enrichment p-value:

0.455

your network does not have significantly more
interactions than expected (what does that mean?)

Functional enrichments in your networkNote: some enrichments may be expected here (why?)
disable highlight explain columns

Biological Process (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0006351

Transcription, DNA-templated

6 of 143

1.62

2.02

8.08e-06

GO:0006383

Transcription by RNA polymerase III

3 of 19

2.19

1.83

0.00030

GO:0009059

Macromolecule biosynthetic process

8 of 669

1.07

1.13

2.36e-05

GO:0044271

Cellular nitrogen compound biosynthetic process

8 of 730

1.03

1.05

3.71e-05

GO:0044249

Cellular biosynthetic process

9 of 1207

0.87

0.82

6.18e-05

(more ...)

Molecular Function (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0003677

DNA binding

7 of 547

1.1

1.02

0.00035

Cellular Component (Gene Ontology)

GO-term

description

count in network

strength

signal

false discovery rate

GO:0000127

Transcription factor TFIIIC complex

3 of 4

2.87

2.73

1.00e-05

GO:0005667

Transcription regulator complex

5 of 71

1.84

2.37

4.89e-06

GO:0000428

DNA-directed RNA polymerase complex

3 of 81

1.56

0.94

0.0104

GO:0005763

Mitochondrial small ribosomal subunit

2 of 29

1.83

0.73

0.0394

GO:0032991

Protein-containing complex

9 of 1827

0.69

0.56

0.00083

Local Network Cluster (STRING)

cluster

description

count in network

strength

signal

false discovery rate

CL:3529

RNA Polymerase III Transcription Initiation From Type 1 Promoter

4 of 18

2.34

2.71

5.93e-06

CL:3271

Transcription, DNA-templated, and Mediator complex

5 of 160

1.49

1.51

0.00016

CL:3532

RNA polymerase III complex, and Transcription factor TFIIIB complex

2 of 12

2.21

0.87

0.0241

Reactome Pathways

pathway

description

count in network

strength

signal

false discovery rate

MAP-76066

RNA Polymerase III Transcription Initiation From Type 2 Promoter

6 of 24

2.39

4.91

1.09e-10

MAP-76061

RNA Polymerase III Transcription Initiation From Type 1 Promoter

6 of 24

2.39

4.91

1.09e-10

MAP-76046

RNA Polymerase III Transcription Initiation

6 of 27

2.34

4.84

1.09e-10

MAP-74158

RNA Polymerase III Transcription

6 of 27

2.34

4.84

1.09e-10

MAP-74160

Gene expression (Transcription)

7 of 606

1.06

1.04

8.76e-05

Enrichment display settings

Enrichment analysis is still ongoing, please wait ...

Server load: low (16%) [HD]

Permalink

Network

Neighborhood

Experiments

Fusion

Databases

Cooccurrence

Textmining

Coexpression

© STRING Consortium 2024

Credits

Access

Info

About