STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCL_09037tRNA_int_end_N2 domain-containing protein. (494 aa)    
Predicted Functional Partners:
VFPFJ_08902
tRNA-splicing endonuclease subunit Sen34; Constitutes one of the two catalytic subunit of the tRNA- splicing endonuclease complex, a complex responsible for identification and cleavage of the splice sites in pre-tRNA. It cleaves pre-tRNA at the 5'- and 3'-splice sites to release the intron. The products are an intron and two tRNA half-molecules bearing 2',3'-cyclic phosphate and 5'-OH termini. There are no conserved sequences at the splice sites, but the intron is invariably located at the same site in the gene, placing the splice sites an invariant distance from the constant structura [...]
   
 0.838
CLP1
mRNA cleavage and polyadenylation factor CLP1; Required for endonucleolytic cleavage during polyadenylation- dependent pre-mRNA 3'-end formation.
    
 0.662
PCL_00074
tRNA-splicing endonuclease subunit Sen15.
    
 
 0.641
VFPFJ_06724
tRNA(M5U54)methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.
   
    0.622
PCL_00836
tRNA ligase.
      
 0.618
VFPBJ_07574
tRNA-splicing endonuclease subunit Sen2.
      
 0.606
VFPFJ_10123
Protein CFT1.
     
 0.465
PCL_06108
Ribosomal protein L16, L13 family; Belongs to the universal ribosomal protein uL13 family.
      
 0.448
PCL_09232
Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.410
VFPFJ_03240
Arginyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family.
      
 0.410
Your Current Organism:
Purpureocillium lilacinum
NCBI taxonomy Id: 33203
Other names: ATCC 10114, CBS 284.36, CCRC 31616, CCRC:31616, DSM 846, IMI 027830, JCM 9332, NCTC 584, NRRL 895, P. lilacinum, Paecilomyces lilacinum, Paecilomyces lilacinus, Penicillium lilacinum, Purpureocillium lilacinum (Thom) Luangsa-ard, Houbraken, Hywel-Jones & Samson 2011, QM 7592, VKM F-3193
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