STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lcsNCytochrome P450 monooxygenase lcsN; Cytochrome P450 monooxygenase; part of the gene cluster that mediates the biosynthesis of the lipopeptide antibiotics leucinostatins that show extensive biological activities, including antimalarial, antiviral, antibacterial, antifungal, and antitumor activities, as well as phytotoxic. Leucinostatin A contains nine amino acid residues, including the unusual amino acid 4-methyl-L-proline (MePro), 2-amino-6-hydroxy-4-methyl-8-oxodecanoic acid (AHyMeOA), 3- hydroxyleucine (HyLeu), alpha-aminoisobutyric acid (AIB), beta-Ala, a 4-methylhex-2-enoic acid at [...] (336 aa)    
Predicted Functional Partners:
PCL_10612
Cytochrome P450 78A3.
 
 
   0.525
VFPBJ_05952
Cytochrome P450 alkane hydroxylase.
 
 
   0.524
VFPFJ_11120
Cytochrome p450 domain-containing protein; Belongs to the cytochrome P450 family.
  
 
   0.517
VFPBJ_07570
Cytochrome P450 3 monooxygenase; Belongs to the cytochrome P450 family.
  
 
  0.515
VFPFJ_00542
Cytochrome p450.
 
     0.495
VFPFJ_07539
Cytochrome p450 domain-containing protein.
  
     0.493
PCL_06441
Cytochrome P450 4F8; Belongs to the cytochrome P450 family.
  
     0.414
VFPFJ_03311
Mediator of RNA polymerase II transcription subunit 14; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors.
    
 0.409
VFPFJ_00182
O-methylsterigmatocystin oxidoreductase; Belongs to the cytochrome P450 family.
  
 
  0.408
VFPFJ_07517
Trichodiene oxygenase.
  
     0.405
Your Current Organism:
Purpureocillium lilacinum
NCBI taxonomy Id: 33203
Other names: ATCC 10114, CBS 284.36, CCRC 31616, CCRC:31616, DSM 846, IMI 027830, JCM 9332, NCTC 584, NRRL 895, P. lilacinum, Paecilomyces lilacinum, Paecilomyces lilacinus, Penicillium lilacinum, Purpureocillium lilacinum (Thom) Luangsa-ard, Houbraken, Hywel-Jones & Samson 2011, QM 7592, VKM F-3193
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