STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
PCL_11774mRNA binding post-transcriptional regulator. (387 aa)    
Predicted Functional Partners:
PCL_02836
DEAD/DEAH box helicase.
   
 
 0.936
VFPFJ_08587
U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region.
   
 0.908
VFPBJ_03565
U1 small nuclear ribonucleoprotein.
   
 0.896
VFPFJ_01581
Rbm25 protein.
    
 
 0.890
VFPFJ_01229
Nuclear cap-binding protein subunit 2.
    
 0.877
PCL_09894
Translation Initiation Factor Eif4e; Belongs to the eukaryotic initiation factor 4E family.
    
 0.865
VFPFJ_07096
PAB1 binding protein.
    
 
 0.861
VFPBJ_03052
U2 snRNP auxilliary factor, large subunit, splicing factor.
    
 0.860
PCL_00562
Cap binding protein.
    
 0.855
VFPFJ_01743
Branchpoint-bridging protein.
    
 
 0.845
Your Current Organism:
Purpureocillium lilacinum
NCBI taxonomy Id: 33203
Other names: ATCC 10114, CBS 284.36, CCRC 31616, CCRC:31616, DSM 846, IMI 027830, JCM 9332, NCTC 584, NRRL 895, P. lilacinum, Paecilomyces lilacinum, Paecilomyces lilacinus, Penicillium lilacinum, Purpureocillium lilacinum (Thom) Luangsa-ard, Houbraken, Hywel-Jones & Samson 2011, QM 7592, VKM F-3193
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