node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM58144.1 | SDM72404.1 | SAMN04487766_10462 | SAMN04487766_10635 | Indole-3-glycerol phosphate synthase. | Anthranilate synthase component 2. | 0.996 |
SDM58144.1 | SDM72438.1 | SAMN04487766_10462 | SAMN04487766_10636 | Indole-3-glycerol phosphate synthase. | Anthranilate synthase, component I. | 0.996 |
SDM58144.1 | ilvA | SAMN04487766_10462 | SAMN04487766_10937 | Indole-3-glycerol phosphate synthase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.448 |
SDM58144.1 | lgt | SAMN04487766_10462 | SAMN04487766_10463 | Indole-3-glycerol phosphate synthase. | Prolipoprotein diacylglyceryl transferase; Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins; Belongs to the Lgt family. | 0.919 |
SDM58144.1 | trpA | SAMN04487766_10462 | SAMN04487766_10632 | Indole-3-glycerol phosphate synthase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.999 |
SDM58144.1 | trpB | SAMN04487766_10462 | SAMN04487766_10633 | Indole-3-glycerol phosphate synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family. | 0.979 |
SDM58144.1 | trpB-2 | SAMN04487766_10462 | SAMN04487766_10637 | Indole-3-glycerol phosphate synthase. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.995 |
SDM58144.1 | trpD | SAMN04487766_10462 | SAMN04487766_10634 | Indole-3-glycerol phosphate synthase. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.992 |
SDM72404.1 | SDM58144.1 | SAMN04487766_10635 | SAMN04487766_10462 | Anthranilate synthase component 2. | Indole-3-glycerol phosphate synthase. | 0.996 |
SDM72404.1 | SDM72438.1 | SAMN04487766_10635 | SAMN04487766_10636 | Anthranilate synthase component 2. | Anthranilate synthase, component I. | 0.999 |
SDM72404.1 | trpA | SAMN04487766_10635 | SAMN04487766_10632 | Anthranilate synthase component 2. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.994 |
SDM72404.1 | trpB | SAMN04487766_10635 | SAMN04487766_10633 | Anthranilate synthase component 2. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family. | 0.999 |
SDM72404.1 | trpB-2 | SAMN04487766_10635 | SAMN04487766_10637 | Anthranilate synthase component 2. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |
SDM72404.1 | trpD | SAMN04487766_10635 | SAMN04487766_10634 | Anthranilate synthase component 2. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
SDM72438.1 | SDM58144.1 | SAMN04487766_10636 | SAMN04487766_10462 | Anthranilate synthase, component I. | Indole-3-glycerol phosphate synthase. | 0.996 |
SDM72438.1 | SDM72404.1 | SAMN04487766_10636 | SAMN04487766_10635 | Anthranilate synthase, component I. | Anthranilate synthase component 2. | 0.999 |
SDM72438.1 | glyA | SAMN04487766_10636 | SAMN04487766_11410 | Anthranilate synthase, component I. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.410 |
SDM72438.1 | trpA | SAMN04487766_10636 | SAMN04487766_10632 | Anthranilate synthase, component I. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.982 |
SDM72438.1 | trpB | SAMN04487766_10636 | SAMN04487766_10633 | Anthranilate synthase, component I. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine; Belongs to the TrpC family. | 0.999 |
SDM72438.1 | trpB-2 | SAMN04487766_10636 | SAMN04487766_10637 | Anthranilate synthase, component I. | Tryptophan synthase beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.999 |