STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SDM95010.1Transcriptional regulator, LacI family. (336 aa)    
Predicted Functional Partners:
SDM23410.1
PTS system, beta-glucosides-specific IIC component.
    
 0.663
SDM51940.1
PTS system, beta-glucosides-specific IIC component.
    
 0.663
SDM60944.1
PTS system, sucrose-specific IIC component.
    
 0.663
SDM74505.1
PTS system, beta-glucosides-specific IIC component.
    
 0.663
SDM42127.1
Phosphocarrier protein.
    
   0.551
SDM95032.1
Peptide/nickel transport system substrate-binding protein.
  
    0.517
ribBA
3,4-dihydroxy 2-butanone 4-phosphate synthase / GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
    
   0.495
pheT
phenylalanyl-tRNA synthetase beta subunit; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
    
   0.465
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
    
   0.448
SDM94982.1
Methyltransferase domain-containing protein.
       0.448
Your Current Organism:
Actinomyces ruminicola
NCBI taxonomy Id: 332524
Other names: A. ruminicola, Actinomyces ruminicola An et al. 2006 emend. Nouioui et al. 2018, CGMCC 1.5030, DSM 27982, JCM 13352, strain B71
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.