node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SDM74178.1 | SDN06402.1 | SAMN04487766_10692 | SAMN04487766_1129 | Phosphoserine phosphatase. | Branched-chain amino acid aminotransferase. | 0.436 |
SDM74178.1 | SDN30118.1 | SAMN04487766_10692 | SAMN04487766_1232 | Phosphoserine phosphatase. | Threonine synthase. | 0.460 |
SDM74178.1 | glyA | SAMN04487766_10692 | SAMN04487766_11410 | Phosphoserine phosphatase. | Glycine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.971 |
SDM74178.1 | ilvA | SAMN04487766_10692 | SAMN04487766_10937 | Phosphoserine phosphatase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.935 |
SDM74178.1 | metXA | SAMN04487766_10692 | SAMN04487766_10171 | Phosphoserine phosphatase. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.919 |
SDM74178.1 | trpA | SAMN04487766_10692 | SAMN04487766_10632 | Phosphoserine phosphatase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.930 |
SDN06402.1 | SDM74178.1 | SAMN04487766_1129 | SAMN04487766_10692 | Branched-chain amino acid aminotransferase. | Phosphoserine phosphatase. | 0.436 |
SDN06402.1 | SDN06516.1 | SAMN04487766_1129 | SAMN04487766_11213 | Branched-chain amino acid aminotransferase. | Acetolactate synthase, small subunit. | 0.804 |
SDN06402.1 | SDN06535.1 | SAMN04487766_1129 | SAMN04487766_11214 | Branched-chain amino acid aminotransferase. | Acetolactate synthase, large subunit. | 0.850 |
SDN06402.1 | SDN30118.1 | SAMN04487766_1129 | SAMN04487766_1232 | Branched-chain amino acid aminotransferase. | Threonine synthase. | 0.692 |
SDN06402.1 | ilvA | SAMN04487766_1129 | SAMN04487766_10937 | Branched-chain amino acid aminotransferase. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.980 |
SDN06402.1 | ldh | SAMN04487766_1129 | SAMN04487766_107116 | Branched-chain amino acid aminotransferase. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.939 |
SDN06402.1 | leuB | SAMN04487766_1129 | SAMN04487766_11210 | Branched-chain amino acid aminotransferase. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.763 |
SDN06402.1 | metXA | SAMN04487766_1129 | SAMN04487766_10171 | Branched-chain amino acid aminotransferase. | Homoserine O-acetyltransferase; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. | 0.424 |
SDN06516.1 | SDN06402.1 | SAMN04487766_11213 | SAMN04487766_1129 | Acetolactate synthase, small subunit. | Branched-chain amino acid aminotransferase. | 0.804 |
SDN06516.1 | SDN06535.1 | SAMN04487766_11213 | SAMN04487766_11214 | Acetolactate synthase, small subunit. | Acetolactate synthase, large subunit. | 0.999 |
SDN06516.1 | SDN30118.1 | SAMN04487766_11213 | SAMN04487766_1232 | Acetolactate synthase, small subunit. | Threonine synthase. | 0.617 |
SDN06516.1 | ilvA | SAMN04487766_11213 | SAMN04487766_10937 | Acetolactate synthase, small subunit. | Threonine dehydratase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.994 |
SDN06516.1 | ldh | SAMN04487766_11213 | SAMN04487766_107116 | Acetolactate synthase, small subunit. | L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family. | 0.939 |
SDN06516.1 | leuB | SAMN04487766_11213 | SAMN04487766_11210 | Acetolactate synthase, small subunit. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 2 subfamily. | 0.994 |