STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
AFLA_002900Polyketide synthase, putative. (2432 aa)    
Predicted Functional Partners:
AFLA_009120
NRPS-like enzyme, putative.
 0.643
AFLA_027360
Prenyltransferase, putative.
      
 0.595
AFLA_125630
PKS-like enzyme, putative.
 
     0.546
AFLA_045510
Integral membrane protein.
      
 0.445
AFLA_067870
Uncharacterized protein.
      
 0.445
AFLA_079360
PKS-like enzyme, putative.
  
     0.414
AFLA_046430
AflYg/ npgA protein, putative.
   
 0.409
agiA
S-adenosyl-L-methionine-dependent N-methyltransferase; Nonribosomal peptide synthase; part of the gene cluster that mediates the biosynthesis of the aspergillicins A and F, 2 cryptic cyclic hexa-depsipeptides. The hexamodular NRPS agiA catalyzes the condensation of the six amino acid residues including N- Me-L-O-Me-tyrosine, L-proline 1, L-proline 2, D-isoleucine, O-acetyl- threonine, and L-isoleucine. The starting condensation domain (C1) of agiA probably loads acetyl-CoA which is condensed on the N-terminus of threonine by the first module to yield O-acetyl-threonine. The second modu [...]
 
 0.402
Your Current Organism:
Aspergillus flavus
NCBI taxonomy Id: 332952
Other names: A. flavus NRRL3357, Aspergillus flavus NRRL3357
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