STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ahcYAdenosylhomocysteinase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (435 aa)    
Predicted Functional Partners:
KYG73732.1
Hypothetical protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.972
KYG77866.1
Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
 
 0.950
metZ
O-succinylhomoserine sulfhydrylase; Catalyzes the formation of L-homocysteine from O-succinyl-L- homoserine (OSHS) and hydrogen sulfide.
   
 0.900
KYG73461.1
Cystathionine gamma-synthase; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 0.895
KYG73520.1
Bifunctional aspartokinase I/homoserine dehydrogenase I; Derived by automated computational analysis using gene prediction method: Protein Homology.
   
 
 0.867
metK
S-adenosylmethionine synthase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.
 
 
 0.832
guaB
IMP dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family.
   
  
 0.725
KYG73731.1
5,10-methylenetetrahydrofolate reductase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the methylenetetrahydrofolate reductase family.
  
 
 0.671
KYG75970.1
Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+.
       0.631
KYG77700.1
Serine dehydratase; Derived by automated computational analysis using gene prediction method: Protein Homology.
     
 0.609
Your Current Organism:
Roseivirga spongicola
NCBI taxonomy Id: 333140
Other names: Flexibacteraceae bacterium UST030701-084, JCM 13337, NRRL B-41219, R. spongicola, Roseivirga spongicola Lau et al. 2006 emend. Hahnke et al. 2016, strain UST030701-084
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