Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (324 aa)    
Predicted Functional Partners:
FMG_0317
Aspartate kinase; Belongs to the aspartokinase family.
 
 
 0.998
FMG_0319
Homoserine dehydrogenase.
 
 0.996
thrB
Threonine synthase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.
  
 
 0.962
aroK
Shikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family.
  
 
 0.727
lysS
lysyl-tRNA synthetase class II; Belongs to the class-II aminoacyl-tRNA synthetase family.
  
 
 0.706
FMG_1001
Pyruvate kinase; Belongs to the pyruvate kinase family.
  
 
 0.574
purD
Phosphoribosylformylglycinamidine synthase; Belongs to the GARS family.
  
  
 0.563
pnp
Polyribonucleotide nucleotidyltransferase; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction.
      0.534
tsaD
Putative o-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
 
 0.530
guaA
GMP synthase; Catalyzes the synthesis of GMP from XMP.
  
  
 0.515
Your Current Organism:
Finegoldia magna ATCC 29328
NCBI taxonomy Id: 334413
Other names: F. magna ATCC 29328, Finegoldia magna str. ATCC 29328, Finegoldia magna strain ATCC 29328
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