| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FMG_0296 | nadD | FMG_0296 | FMG_0369 | Transcriptional regulator Sir2 family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.925 |
| FMG_0296 | nadE | FMG_0296 | FMG_0894 | Transcriptional regulator Sir2 family. | NH(3)-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.917 |
| FMG_0296 | nadK | FMG_0296 | FMG_1027 | Transcriptional regulator Sir2 family. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.913 |
| FMG_0368 | FMG_0370 | FMG_0368 | FMG_0370 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.932 |
| FMG_0368 | aroK | FMG_0368 | FMG_1238 | Conserved hypothetical protein. | Shikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | 0.578 |
| FMG_0368 | nadD | FMG_0368 | FMG_0369 | Conserved hypothetical protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.950 |
| FMG_0368 | obg | FMG_0368 | FMG_0367 | Conserved hypothetical protein. | Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.832 |
| FMG_0370 | FMG_0368 | FMG_0370 | FMG_0368 | Conserved hypothetical protein. | Conserved hypothetical protein. | 0.932 |
| FMG_0370 | aroK | FMG_0370 | FMG_1238 | Conserved hypothetical protein. | Shikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | 0.703 |
| FMG_0370 | nadD | FMG_0370 | FMG_0369 | Conserved hypothetical protein. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.996 |
| FMG_0370 | obg | FMG_0370 | FMG_0367 | Conserved hypothetical protein. | Putative GTP-binding protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. | 0.814 |
| FMG_0398 | cinA | FMG_0398 | FMG_1621 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Competence-damage inducible protein; Belongs to the CinA family. | 0.566 |
| FMG_0398 | nadD | FMG_0398 | FMG_0369 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.946 |
| FMG_0398 | nadE | FMG_0398 | FMG_0894 | Nicotinate phosphoribosyltransferase; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. | NH(3)-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.638 |
| FMG_0880 | aroK | FMG_0880 | FMG_1238 | Bifunctional aldolase-pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Shikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | 0.495 |
| FMG_0880 | nadD | FMG_0880 | FMG_0369 | Bifunctional aldolase-pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.636 |
| FMG_0880 | nadE | FMG_0880 | FMG_0894 | Bifunctional aldolase-pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | NH(3)-dependent NAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. | 0.551 |
| FMG_0880 | nadK | FMG_0880 | FMG_1027 | Bifunctional aldolase-pyrophosphokinase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. | Inorganic polyphosphate/ATP-NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. | 0.436 |
| aroK | FMG_0368 | FMG_1238 | FMG_0368 | Shikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | Conserved hypothetical protein. | 0.578 |
| aroK | FMG_0370 | FMG_1238 | FMG_0370 | Shikimate 5-dehydrogenase; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate dehydrogenase family. | Conserved hypothetical protein. | 0.703 |